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phospho-RPS6KA2 [nucleoplasm]
Stable Identifier
R-CFA-199871
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
p-4S,T356,T570-RPS6KA2, A0A8I3MV42
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
Senescence-Associated Secretory Phenotype (SASP) (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Innate Immune System (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (q) signalling events (Canis familiaris)
Gastrin-CREB signalling pathway via PKC and MAPK (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Nuclear Events (kinase and transcription factor activation) (Canis familiaris)
CREB phosphorylation (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
ERK/MAPK targets (Canis familiaris)
ERK1/2/5 activate RSK1/2/3 (Canis familiaris)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
phospho-RPS6KA2 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MV42
Gene Names
RPS6KA2
Reference Genes
ENSEMBL:ENSCAFG00845004742.1
UCSC:A0A8I3MV42 RPS6KA2
Other Identifiers
612448
CfaAffx.2186.1.S1_s_at
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0004711
GO:0004712
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0006468
GO:0008285
GO:0016301
GO:0016740
GO:0035556
GO:0043065
GO:0045786
GO:0140096
Participates
as a member of
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Canis familiaris)
Other forms of this molecule
RPS6KA2 [nucleoplasm]
phospho-RPS6KA2 [cytosol]
phospho-RPS6KA2 [nucleoplasm]
Inferred From
p-4S,T356,T570-RPS6KA2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 218 (in Homo sapiens)
Coordinate
218
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 360 (in Homo sapiens)
Coordinate
360
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 377 (in Homo sapiens)
Coordinate
377
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 730 (in Homo sapiens)
Coordinate
730
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 356 (in Homo sapiens)
Coordinate
356
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 570 (in Homo sapiens)
Coordinate
570
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
ENSEMBL
ENSCAFT00845008526
,
ENSCAFG00845004742
,
ENSCAFP00845006728
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