Reactome | CD3G [plasma membrane]

CD3G [plasma membrane]

Stable Identifier

R-CFA-197917

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

CD3G, A0A8I3MFY1

Locations in the PathwayBrowser

Expand all

Immune System (Canis familiaris)

- Adaptive Immune System (Canis familiaris)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Canis familiaris)
    - TCR binds microbial lipid-based antigen via CD1 (Canis familiaris)
      - CD1:B2M:microbial lipid:TCR [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
    - TCR binds self-lipid-based antigen via CD1 (Canis familiaris)
      - CD1:B2M:self-lipid:TCR [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
    - TCR complex interacts with peptide antigen-presenting MHC Class I (Canis familiaris)
      - T-cell receptor complex with CD8 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex with CD8 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
  - TCR signaling (Canis familiaris)
    - Downstream TCR signaling (Canis familiaris)
      - Change of PKC theta conformation (Canis familiaris)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
    - Phosphorylation of CD3 and TCR zeta chains (Canis familiaris)
      - Activation of Lck (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - Dephosphorylation of Lck-pY505 by CD45 (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - Inactivation of LCK by PTPN22 (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - Inactivation of Lck by Csk (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
        
        Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
      - Phosphorylation of ITAM motifs in CD3 complexes (Canis familiaris)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
    - Translocation of ZAP-70 to Immunological synapse (Canis familiaris)
      - Phosphorylation of ZAP-70 by Lck (Canis familiaris)
        
        Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Canis familiaris)
        
        T-cell receptor complex [plasma membrane] (Canis familiaris)
        
        CD3 epsilon gamma [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
- Innate Immune System (Canis familiaris)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
    - FCGR activation (Canis familiaris)
      - Cross-linking of FCGRIA with IgG-coated Ag (Canis familiaris)
        
        FCGRIA:CD3G homodimer [plasma membrane] (Canis familiaris)
        
        CD3G homodimer [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)
        
        IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Canis familiaris)
        
        FCGRIA:CD3G homodimer [plasma membrane] (Canis familiaris)
        
        CD3G homodimer [plasma membrane] (Canis familiaris)
        
        CD3G [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MFY1

Gene Names

CD3G

Reference Genes

BioGPS Gene:489383 CD3G

ENSEMBL:ENSCAFG00845002392.1

KEGG:cfa:489383 CD3G

Monarch:489383 CD3G

NCBI Gene:489383 CD3G

UCSC:A0A8I3MFY1 CD3G

Reference Transcript

Other Identifiers

489383

CfaAffx.19788.1.S1_at

GO:0002250

GO:0002376

GO:0004888

GO:0005829

GO:0005886

GO:0007163

GO:0007166

GO:0009897

GO:0015031

GO:0016020

GO:0042105

GO:0042802

GO:0045059

GO:0070228

Participates

as a member of

AP-2 dileucine-containing cargo [plasma membrane] (Canis familiaris)

as a component of

Other forms of this molecule

phospho-CD3G [plasma membrane]

Inferred From

CD3G [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_013968855.1, XP_005619768.1, XP_038520667.1, XP_038520666.1, XP_038391926.1, XP_038391927.1

ENSEMBL

ENSCAFP00845003374, ENSCAFT00845004223, ENSCAFG00845002392

Cite Us!