Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-8Y-FGFR2-3 [plasma membrane]
Stable Identifier
R-CFA-190412
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
plasma membrane
Synonyms
A0A8I3P6D2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
RAS GEFs [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by FGFR (Canis familiaris)
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
FRS-mediated FGFR2 signaling (Canis familiaris)
Activated FGFR2 binds FRS2 (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 binds FRS3 (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 phosphorylates FRS2 (Canis familiaris)
Activated FGFR2:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-8T-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 phosphorylates FRS3 (Canis familiaris)
Activated FGFR2:FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 phosphorylates PPTN11 (Canis familiaris)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS bind to PPTN11 (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:pFRS binds GRB2:SOS1 (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS3 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
PI-3K cascade:FGFR2 (Canis familiaris)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Phospholipase C-mediated cascade; FGFR2 (Canis familiaris)
Activated FGFR2 binds PLCG1 (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
activated FGFR2:PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 phosphorylates PLCG1 (Canis familiaris)
activated FGFR2:PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
p-4Y-PLCG1 dissociates from activated FGFR2 (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
SHC-mediated cascade:FGFR2 (Canis familiaris)
Activated FGFR2 binds SHC1 (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2 phosphorylates SHC1 (Canis familiaris)
Activated FGFR2:SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Canis familiaris)
Activated FGFR2:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Canis familiaris)
Activated FGFR2:pY-SHC1 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
FGFR2 ligand binding and activation (Canis familiaris)
FGFR2b ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR2b (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Negative regulation of FGFR2 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Canis familiaris)
Activated FGFR2:FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-8T-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
CBL ubiquitinates FRS2 and FGFR2 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR2 [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2 [plasma membrane] (Canis familiaris)
Activated FGFR [plasma membrane] (Canis familiaris)
Activated FGFR2b homodimer bound to FGF [plasma membrane] (Canis familiaris)
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR2-3 [plasma membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P6D2
Reference Genes
ENSEMBL:ENSCAFG00845019372.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845019372.1
Other Identifiers
415125
Cfa.3626.2.A1_s_at
CfaAffx.19222.1.S1_s_at
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0005007
GO:0005524
GO:0005634
GO:0005737
GO:0005886
GO:0005938
GO:0006468
GO:0008284
GO:0008543
GO:0009986
GO:0010839
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0017134
GO:0023052
GO:0030312
GO:0031012
GO:0036211
GO:0042803
GO:0043226
GO:0043410
GO:0048701
GO:0048856
GO:0060089
GO:0062023
GO:0140096
Participates
as a component of
Activated FGFR2b long homodimer [plasma membrane] (Canis familiaris)
Other forms of this molecule
FGFR2c short [plasma membrane]
FGFR2c long [plasma membrane]
FGFR2b short [plasma membrane]
FGFR2b long [plasma membrane]
phospho-Phosphorylated Fibroblast growth factor receptor 2b short [plasma membrane]
phospho-p-8Y-FGFR2-5 [plasma membrane]
phospho-p-8Y-FGFR2c long [plasma membrane]
Inferred From
p-8Y-FGFR2-3 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 467 (in Homo sapiens)
Coordinate
467
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 587 (in Homo sapiens)
Coordinate
587
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 589 (in Homo sapiens)
Coordinate
589
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 657 (in Homo sapiens)
Coordinate
657
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 658 (in Homo sapiens)
Coordinate
658
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 734 (in Homo sapiens)
Coordinate
734
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 770 (in Homo sapiens)
Coordinate
770
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 780 (in Homo sapiens)
Coordinate
780
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
Ensembl
ENSCAFG00845019372
,
ENSCAFT00845034261
,
ENSCAFP00845026817
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text