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FZR1 [cytosol]
Stable Identifier
R-CFA-174249
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
FZR1, A0A8I3NCA9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Regulation of mitotic cell cycle (Canis familiaris)
APC/C-mediated degradation of cell cycle proteins (Canis familiaris)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Canis familiaris)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Degradation of multiubiquitinated cell cycle proteins (Canis familiaris)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Canis familiaris)
Association of Cdh1 with the APC/C (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Dephosphorylation of phospho-Cdh1 (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Regulation of APC/C activators between G1/S and early anaphase (Canis familiaris)
SCF-beta-TrCP mediated degradation of Emi1 (Canis familiaris)
Ubiquitination of Emi1 by SCF-beta-TrCP (Canis familiaris)
SCF-associated multiubiquitinated Emi1complexes [cytosol] (Canis familiaris)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Canis familiaris)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Canis familiaris)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] (Canis familiaris)
phospho-Emi1:Cdc20/Cdh1 complexes [cytosol] (Canis familiaris)
phospho-Emi1(Ser 145, Ser 149):Cdc20/Cdh1 complexes [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
phospho-Emi1(Ser 182):Cdc20/Cdh1:complexes [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
DNA Replication (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen processing: Ubiquitination & Proteasome degradation (Canis familiaris)
Interaction of E3 with substrate and E2-Ub complex (Canis familiaris)
Ag-substrate:E3:E2:Ub [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Polyubiquitination of substrate (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3:K48-polyubiquitinated substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3:Ub:substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Release of E3 from polyubiquitinated substrate (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3:K48-polyubiquitinated substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
Transfer of Ub from E2 to substrate and release of E2 (Canis familiaris)
Ag-substrate:E3:E2:Ub [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
E3:Ub:substrate [cytosol] (Canis familiaris)
E3 ligases in proteasomal degradation [cytosol] (Canis familiaris)
APC/C E3 ligase complex [cytosol] (Canis familiaris)
Cdc20/Cdh1 [cytosol] (Canis familiaris)
FZR1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NCA9
Gene Names
FZR1
Reference Genes
ENSEMBL:ENSCAFG00845009377.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009377.1 FZR1
Other Identifiers
485059
CfaAffx.29327.1.S1_at
GO:0000278
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0007095
GO:0008284
GO:0010997
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0031145
GO:0031965
GO:0036211
GO:0040020
GO:0043226
GO:0048856
GO:0051603
GO:0060090
GO:0070306
GO:0097027
GO:0098772
GO:0140013
GO:1904668
GO:1990756
GO:2000773
Participates
as an output of
Dephosphorylation of phospho-Cdh1 (Canis familiaris)
as an input of
Association of Cdh1 with the APC/C (Canis familiaris)
as a component of
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
as a member of
Cdc20/Cdh1 [cytosol] (Canis familiaris)
Other forms of this molecule
phospho-FZR1 [cytosol]
phospho-FZR1 [nucleoplasm]
FZR1 [nucleoplasm]
Inferred From
FZR1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000105325
Ensembl
ENSCAFP00845012910
,
ENSCAFT00845016597
,
ENSCAFG00845009377
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