Reactome | LDL [extracellular region]

LDL [extracellular region]

Stable Identifier

R-CFA-171131

Type

Complex

Species

Canis familiaris

Compartment

extracellular region

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

APOB [extracellular region] (Canis familiaris)
x 1500 CHEST [extracellular region]
x 670 CHOL [extracellular region]
x 690 PL [extracellular region]
x 170 TAGs [extracellular region]

Participates

as an input of

LDL + LDLR => LDL:LDLR complex (Canis familiaris)
OLR1 binds to oxidized LDL (Canis familiaris)
LDL binds to LRP8 (Canis familiaris)

as a component of

OLR1 bound to oxidized LDL [plasma membrane] (Canis familiaris)
LDL:p-LRP8 [plasma membrane] (Canis familiaris)
LDL:LRP8 [plasma membrane] (Canis familiaris)

as a member of

Endocytosed Ligands of SCARB1 [extracellular region] (Canis familiaris)
Ligands of SCARB1 [extracellular region] (Canis familiaris)
LDL,HDL [extracellular region] (Canis familiaris)

This entity regulates

Positively

PECAM1 is phosphorylated (Canis familiaris)

Inferred From

LDL [extracellular region] (Homo sapiens)