Reactome | PROC [endoplasmic reticulum lumen]

PROC [endoplasmic reticulum lumen]

Stable Identifier

R-CFA-159768

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum lumen

Synonyms

3D-PROC(33-197), Q28278

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
    - Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Canis familiaris)
      - Gamma-carboxylation of protein precursors (Canis familiaris)
        
        GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Canis familiaris)
        
        pro-protein C, uncarboxylated [endoplasmic reticulum lumen] (Canis familiaris)
        
        PROC [endoplasmic reticulum lumen] (Canis familiaris)

External Reference Information

External Reference

UniProt:Q28278

Gene Names

PROC

Reference Genes

BioGPS Gene:476104 PROC

ENSEMBL:ENSCAFG00845022381

KEGG:cfa:476104 PROC

Monarch:476104 PROC

NCBI Gene:476104 PROC

UCSC:Q28278 PROC

Reference Transcript

Other Identifiers

476104

Cfa.6331.1.A1_at

Cfa.6331.1.A1_s_at

GO:0004252

GO:0005509

GO:0005576

GO:0005783

GO:0005794

GO:0006508

GO:0007596

GO:0007599

GO:0008233

GO:0008236

GO:0016787

GO:0043066

GO:0050728

GO:0050819

GO:1903142

Participates

as a component of

pro-protein C, uncarboxylated [endoplasmic reticulum lumen] (Canis familiaris)

Other forms of this molecule

PROC [Golgi lumen]

PROC [endoplasmic reticulum lumen]

PROC [extracellular region]

phospho-PROC [endoplasmic reticulum lumen]

PROC [endoplasmic reticulum lumen]

PROC [extracellular region]

Inferred From

3D-PROC(33-197) [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,3R)-3-hydroxyaspartic acid at 113 (in Homo sapiens)

Coordinate

113

PsiMod Name

(2S,3R)-3-hydroxyaspartic acid [MOD:00036]

PsiMod Definition

A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid.

Cross References

RefSeq

XP_038281495.1, NP_001013871.1

ENSEMBL

ENSCAFP00845030975, ENSCAFT00845039524, ENSCAFG00845022381

VGNC

45006

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