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lep-2 [cytosol]
Stable Identifier
R-CEL-976042
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
MKRN1, Q9N373
Locations in the PathwayBrowser
Expand all
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
Polyubiquitination of substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
AKT phosphorylates targets in the cytosol (Caenorhabditis elegans)
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN stability and activity (Caenorhabditis elegans)
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
lep-2 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q9N373
Gene Names
lep-2
Reference Genes
BioGPS Gene:176918 lep-2
ENSEMBL:WBGene00002278
KEGG:cel:CELE_Y55F3AM.6 lep-2
Monarch:176918 lep-2
NCBI Gene:176918 lep-2
UCSC:Q9N373 lep-2
Wormbase:WBGene00002278
Wormbase:WBGene00002278 lep-2
Other Identifiers
176918
GO:0000151
GO:0000209
GO:0002119
GO:0003723
GO:0003824
GO:0005737
GO:0006511
GO:0007548
GO:0008270
GO:0016567
GO:0016740
GO:0030154
GO:0042551
GO:0046872
GO:0048856
GO:0061630
GO:0140096
Participates
as an input of
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
phospho-lep-2 [cytosol]
Inferred From
MKRN1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001023510.1
,
NP_001023511.1
ENSEMBL
Y55F3AM.6a.1
,
Y55F3AM.6a.1
,
WBGene00002278
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