Reactome | mask-1 [cytosol]

mask-1 [cytosol]

Stable Identifier

R-CEL-975417-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

ASB10, Q21920

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
    - Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
      - Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
      - Polyubiquitination of substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
      - Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
      - Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        Homologues of ASB10 [cytosol] (Caenorhabditis elegans)
        
        mask-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21920

Gene Names

mask-1

Reference Genes

BioGPS Gene:177927 mask-1

ENSEMBL:WBGene00011240

KEGG:cel:CELE_R11A8.7 mask-1

Monarch:177927 mask-1

NCBI Gene:177927 mask-1

UCSC:Q21920 mask-1

Wormbase:WBGene00011240

Wormbase:WBGene00011240 mask-1

Reference Transcript

Other Identifiers

177927

GO:0003674

GO:0003676

GO:0003723

GO:0005515

GO:0005575

GO:0005737

GO:0008150

Participates

as a member of

Homologues of ASB10 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

mask-1 [cytosol]

Inferred From

ASB10 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001368167.1, NP_001263772.1, NP_501916.2, NP_001255486.1, NP_001122795.1, NP_001122794.1, NP_001263773.1, NP_501915.2

ENSEMBL

R11A8.7a.1, WBGene00011240, R11A8.7a.1

PRO

Q21920

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