Reactome | irk-3 [plasma membrane]

irk-3 [plasma membrane]

Stable Identifier

R-CEL-975336

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

KCNJ4, A0A1C3NSK2

Locations in the PathwayBrowser

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Neuronal System (Caenorhabditis elegans)

- Potassium Channels (Caenorhabditis elegans)
  - Inwardly rectifying K+ channels (Caenorhabditis elegans)
    - Classical Kir channels (Caenorhabditis elegans)
      - KCNJs transport K+ from the extracellular region to cytosol (Caenorhabditis elegans)
        
        KCNJ tetramer [plasma membrane] (Caenorhabditis elegans)
        
        KCNJs [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
    - G protein gated Potassium channels (Caenorhabditis elegans)
      - Activation of G protein gated Potassium channels (Caenorhabditis elegans)
        
        Activation of GIRK/Kir3 Channels (Caenorhabditis elegans)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Caenorhabditis elegans)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
- Transmission across Chemical Synapses (Caenorhabditis elegans)
  - Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
    - GABA receptor activation (Caenorhabditis elegans)
      - GABA B receptor activation (Caenorhabditis elegans)
        
        Activation of GABAB receptors (Caenorhabditis elegans)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Caenorhabditis elegans)
        
        Activation of GIRK/Kir3 Channels (Caenorhabditis elegans)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Caenorhabditis elegans)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)
        
        Kir heterotetramers [plasma membrane] (Caenorhabditis elegans)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Caenorhabditis elegans)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)
        
        irk-3 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:A0A1C3NSK2

Gene Names

irk-3

Reference Genes

BioGPS Gene:191696 irk-3

ENSEMBL:WBGene00002151

Monarch:191696 irk-3

NCBI Gene:191696 irk-3

UCSC:A0A1C3NSK2 irk-3

Wormbase:WBGene00002151

Wormbase:WBGene00002151 irk-3

Reference Transcript

RefSeq:NM_001381146.1 irk-3

Other Identifiers

191696

GO:0005242

GO:0005886

GO:0006811

GO:0006813

GO:0007614

GO:0016020

GO:0034220

GO:0034702

GO:0034765

GO:0050877

GO:0055085

GO:0071805

GO:0098655

GO:1990573

Participates

as a member of

Homologues of KCNJ4 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

irk-3 [plasma membrane]

Inferred From

KCNJ4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001368607.1

ENSEMBL

WBGene00002151, K04G11.5c.1, K04G11.5c.1

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