Reactome | vha-17 [lysosomal membrane]

vha-17 [lysosomal membrane]

Stable Identifier

R-CEL-9640180

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

lysosomal membrane

Synonyms

ATP6V0E1, Q20591

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - Cellular response to starvation (Caenorhabditis elegans)
    - Amino acids regulate mTORC1 (Caenorhabditis elegans)
      - RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - RRAGA,B hydrolyzes GTP (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - RRAGC,D exchanges GTP for GDP (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - RRAGC,D hydrolyzes GTP (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - mTORC1 binds RHEB:GTP (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase:Ragulator [lysosomal membrane] (Caenorhabditis elegans)
        
        v-ATPase [lysosomal membrane] (Caenorhabditis elegans)
        
        ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)
        
        vha-17 [lysosomal membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q20591

Gene Names

vha-17

Reference Genes

BioGPS Gene:177757 vha-17

ENSEMBL:WBGene00009882

KEGG:cel:CELE_F49C12.13 vha-17

Monarch:177757 vha-17

NCBI Gene:177757 vha-17

UCSC:Q20591 vha-17

Wormbase:WBGene00009882

Wormbase:WBGene00009882 vha-17

Reference Transcript

RefSeq:NM_069235.10 vha-17

Other Identifiers

177757

GO:0005886

GO:0006811

GO:0009792

GO:0010172

GO:0016020

GO:0016324

GO:0033179

GO:0033181

GO:0043296

GO:0046961

GO:0048856

GO:0055085

GO:0060142

GO:1902600

Participates

as a component of

ATP6V0 [lysosomal membrane] (Caenorhabditis elegans)

Other forms of this molecule

vha-17 [phagocytic vesicle membrane]

vha-17 [endosome membrane]

Inferred From

ATP6V0E [lysosomal membrane] (Homo sapiens)

ATP6V0E2 [lysosomal membrane] (Homo sapiens)

ATP6V0E1 [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_501636.2

ENSEMBL

F49C12.13.1, WBGene00009882, F49C12.13.1

PRO

Q20591

Cite Us!