Reactome | SYT2 [clathrin-coated endocytic vesicle membrane]

SYT2 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-CEL-8869116

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

G5EDP5

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - Clathrin-mediated endocytosis (Caenorhabditis elegans)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
    - RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        Homologues of SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EDP5

Reference Genes

BioGPS Gene:3565199 Q19016

CTD Gene:3565199 Q19016

ENSEMBL:WBGene00008438

KEGG:cel:CELE_DH11.5

Monarch:3565199 Q19016

NCBI Gene:3565199 Q19016

UCSC:G5EDP5

Wormbase:WBGene00008438

Wormbase:WBGene00008438 Q19016

Reference Transcript

RefSeq:NM_001267202.1

Other Identifiers

3565199

GO:0000149

GO:0005515

GO:0005544

GO:0005886

GO:0016192

GO:0017158

GO:0030424

GO:0030672

GO:0031045

GO:0031410

GO:0061891

GO:0070382

GO:0099502

GO:2000300

Participates

as a member of

Homologues of SYT2 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Other forms of this molecule

SYT8 [clathrin-coated endocytic vesicle membrane]

SYT8 [plasma membrane]

SYT2 [plasma membrane]

Inferred From

SYT2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001254131.1

ENSEMBL

DH11.5d.1, DH11.5d.1, WBGene00008438

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