Reactome | rps-28 [cytosol]

rps-28 [cytosol]

Stable Identifier

R-CEL-72365

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPS28, Q95Y04

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-28 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-28 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-28 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-28 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-28 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q95Y04

Gene Names

rps-28

Reference Genes

BioGPS Gene:176975 rps-28

CTD Gene:176975 rps-28

ENSEMBL:WBGene00004497

KEGG:cel:CELE_Y41D4B.5 rps-28

Monarch:176975 rps-28

NCBI Gene:176975 rps-28

UCSC:Q95Y04 rps-28

Wormbase:WBGene00004497

Wormbase:WBGene00004497 rps-28

Other Identifiers

176975

GO:0000028

GO:0002181

GO:0003735

GO:0005198

GO:0005737

GO:0005783

GO:0005791

GO:0005829

GO:0005840

GO:0006412

GO:0022627

GO:0030490

GO:0065003

GO:0098556

GO:1990904

Participates

as a component of

Other forms of this molecule

rps-28 [nucleoplasm]

Inferred From

RPS28 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001370541.1

ENSEMBL

Y41D4B.5.1, WBGene00004497, Y41D4B.5.1

PRO

Q95Y04

PDB

9BH5, 9CAI

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