Reactome | rps-27 [cytosol]

rps-27 [cytosol]

Stable Identifier

R-CEL-72361

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPS27, Q9TXP0

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-27 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-27 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-27 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-27 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-27 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9TXP0

Gene Names

rps-27

Reference Genes

BioGPS Gene:178538 rps-27

CTD Gene:178538 rps-27

ENSEMBL:WBGene00004496

KEGG:cel:CELE_F56E10.4 rps-27

Monarch:178538 rps-27

NCBI Gene:178538 rps-27

UCSC:Q9TXP0 rps-27

Wormbase:WBGene00004496

Wormbase:WBGene00004496 rps-27

Reference Transcript

RefSeq:NM_001383266.2 rps-27

Other Identifiers

178538

GO:0000028

GO:0003723

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0008270

GO:0022627

GO:0046872

GO:0065003

GO:1990904

Participates

as a component of

Other forms of this molecule

rps-27 [nucleoplasm]

rps-27 [cytosol]

Inferred From

RPS27,RPS27L [cytosol] (Homo sapiens)

RPS27 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001370756.1

ENSEMBL

F56E10.4.1, F56E10.4.2, WBGene00004496, F56E10.4.1, F56E10.4.2

PRO

Q9TXP0

PDB

9BH5, 9CAI

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