Reactome | rps-17 [cytosol]

rps-17 [cytosol]

Stable Identifier

R-CEL-72339

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPS17, O01692

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-17 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-17 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-17 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-17 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-17 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O01692

Gene Names

rps-17

Reference Genes

BioGPS Gene:172313 rps-17

ENSEMBL:WBGene00004486

KEGG:cel:CELE_T08B2.10 rps-17

Monarch:172313 rps-17

NCBI Gene:172313 rps-17

UCSC:O01692 rps-17

Wormbase:WBGene00004486

Wormbase:WBGene00004486 rps-17

Reference Transcript

RefSeq:NM_059394.9 rps-17

Other Identifiers

172313

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0022626

GO:0022627

GO:1990904

Participates

as a component of

Other forms of this molecule

rps-17 [nucleoplasm]

Inferred From

RPS17 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_491795.1

ENSEMBL

WBGene00004486, T08B2.10.1, T08B2.10.1

PRO

O01692

PDB

9BH5, 9CAI

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