Reactome | rsp-3 [nucleoplasm]

rsp-3 [nucleoplasm]

Stable Identifier

R-CEL-72031

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

SRSF1, Q9NEW6

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Processing of Capped Intron-Containing Pre-mRNA (Caenorhabditis elegans)
  - Formation of pre-mRNPs (Caenorhabditis elegans)
    - Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
      - shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
      - Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
  - Transport of Mature Transcript to Cytoplasm (Caenorhabditis elegans)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Caenorhabditis elegans)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Caenorhabditis elegans)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Caenorhabditis elegans)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA 3'-end processing (Caenorhabditis elegans)
    - mRNA Polyadenylation (Caenorhabditis elegans)
      - Core CPA complex binds capped pre-mRNA (Caenorhabditis elegans)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - PP1 dephosphorylates RNA Pol II (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - RBBP6 activates CPSF complex (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA Splicing (Caenorhabditis elegans)
    - mRNA Splicing - Major Pathway (Caenorhabditis elegans)
      - Formation of the Spliceosomal Bact complex (Caenorhabditis elegans)
        
        Spliceosomal B complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal Bact complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal C complex containing intron lariat (Caenorhabditis elegans)
        
        Spliceosomal B* complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal C* complex (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal P complex and exon ligation (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal P complex [nucleoplasm] (Caenorhabditis elegans)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
    - mRNA Splicing - Minor Pathway (Caenorhabditis elegans)
      - ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Caenorhabditis elegans)
        
        ATAC C Complex [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of AT-AC B Complex (Caenorhabditis elegans)
        
        ATAC A Complex [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        ATAC B Complex [nucleoplasm] (Caenorhabditis elegans)
        
        ATAC A Complex [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of AT-AC C complex (Caenorhabditis elegans)
        
        ATAC B Complex [nucleoplasm] (Caenorhabditis elegans)
        
        ATAC A Complex [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)
        
        ATAC C Complex [nucleoplasm] (Caenorhabditis elegans)
        
        rsp-3 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9NEW6

Gene Names

rsp-3

Reference Genes

BioGPS Gene:176688 rsp-3

ENSEMBL:WBGene00004700

KEGG:cel:CELE_Y111B2A.18 rsp-3

Monarch:176688 rsp-3

NCBI Gene:176688 rsp-3

UCSC:Q9NEW6 rsp-3

Wormbase:WBGene00004700

Wormbase:WBGene00004700 rsp-3

Reference Transcript

RefSeq:NM_001383015.1 rsp-3

Other Identifiers

176688

GO:0000381

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0006376

GO:0006397

GO:0008380

GO:0009792

GO:0016071

GO:0016607

GO:0048856

GO:0065003

Participates

as a component of

as a member of

shuttling SRSFs [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

rsp-3 [nucleoplasm]

Inferred From

SRSF1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001370111.1

ENSEMBL

Y111B2A.18.2, Y111B2A.18.1, WBGene00004700, Y111B2A.18.2, Y111B2A.18.1

PRO

Q9NEW6

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