Reactome | efl-1 [nucleoplasm]

efl-1 [nucleoplasm]

Stable Identifier

R-CEL-68669-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

E2F5, G5EF11

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
        
        SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Caenorhabditis elegans)
        
        RBL1:E2F4/5:DP1/2 [nucleoplasm] (Caenorhabditis elegans)
        
        E2F4,E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        efl-1 [nucleoplasm] (Caenorhabditis elegans)
        
        p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 [nucleoplasm] (Caenorhabditis elegans)
        
        RBL1:E2F4/5:DP1/2 [nucleoplasm] (Caenorhabditis elegans)
        
        E2F4,E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        efl-1 [nucleoplasm] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by TGFB family members (Caenorhabditis elegans)
  - Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
        
        SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Caenorhabditis elegans)
        
        RBL1:E2F4/5:DP1/2 [nucleoplasm] (Caenorhabditis elegans)
        
        E2F4,E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        efl-1 [nucleoplasm] (Caenorhabditis elegans)
        
        p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 [nucleoplasm] (Caenorhabditis elegans)
        
        RBL1:E2F4/5:DP1/2 [nucleoplasm] (Caenorhabditis elegans)
        
        E2F4,E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of E2F5 [nucleoplasm] (Caenorhabditis elegans)
        
        efl-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EF11

Gene Names

efl-1

Reference Genes

BioGPS Gene:180133 efl-1

CTD Gene:180133 efl-1

ENSEMBL:WBGene00001161

KEGG:cel:CELE_Y102A5C.18 efl-1

Monarch:180133 efl-1

NCBI Gene:180133 efl-1

UCSC:G5EF11 efl-1

Wormbase:WBGene00001161

Wormbase:WBGene00001161 efl-1

Reference Transcript

RefSeq:NM_074888.7 efl-1

Other Identifiers

180133

GO:0000978

GO:0000981

GO:0003677

GO:0005515

GO:0005634

GO:0005667

GO:0006355

GO:0006357

GO:0010629

GO:0035189

GO:0040027

GO:0046580

GO:0046599

GO:0046983

GO:0048557

GO:0061629

GO:0070176

GO:0090575

Participates

as a member of

Homologues of E2F5 [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

phospho-efl-1 [nucleoplasm]

efl-1 [nucleoplasm]

phospho-efl-1 [nucleoplasm]

efl-1 [nucleoplasm]

Inferred From

E2F5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_507289.1

ENSEMBL

Y102A5C.18.1, WBGene00001161, Y102A5C.18.1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q22703	2	dpl-1 [nucleoplasm] (R-CEL-68652) dpl-1 [nucleoplasm] (R-CEL-1362225)	0.544	2

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