Reactome | sel-9 [endoplasmic reticulum membrane]

sel-9 [endoplasmic reticulum membrane]

Stable Identifier

R-CEL-5689480

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

endoplasmic reticulum membrane

Synonyms

TMED2, O17528

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPII-mediated vesicle transport (Caenorhabditis elegans)
        
        Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        Loss of SAR1B GTPase (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        Vesicle budding (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        Cargo concentration in the ER (Caenorhabditis elegans)
        
        Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer binds GPI anchored proteins (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPII-mediated vesicle transport (Caenorhabditis elegans)
      - Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
      - Loss of SAR1B GTPase (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
      - Vesicle budding (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
    - Cargo concentration in the ER (Caenorhabditis elegans)
      - Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
      - TMED2:TMED10 tetramer binds GPI anchored proteins (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer:GPI-CD59, GPI-FOLR1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2:TMED10 tetramer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        COPI vesicle uncoating at the ER (Caenorhabditis elegans)
        
        Golgi-to-ER cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        SURF4:p24 complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2 dimer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        Golgi-to-ER cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        SURF4:p24 complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2 dimer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        p24 dimers [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2 dimer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        p24 dimers [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        TMED2 dimer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        sel-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O17528

Gene Names

sel-9

Reference Genes

BioGPS Gene:179213 sel-9

ENSEMBL:WBGene00004766

KEGG:cel:CELE_W02D7.7 sel-9

Monarch:179213 sel-9

NCBI Gene:179213 sel-9

UCSC:O17528 sel-9

Wormbase:WBGene00004766

Wormbase:WBGene00004766 sel-9

Reference Transcript

RefSeq:NM_001383355.2 sel-9

Other Identifiers

179213

GO:0000139

GO:0005783

GO:0005793

GO:0005794

GO:0006886

GO:0006888

GO:0007030

GO:0008593

GO:0012507

GO:0015031

GO:0016020

GO:0016192

GO:0030134

GO:0030659

GO:0030663

GO:0031410

GO:0043226

GO:0051049

Participates

as a component of

Other forms of this molecule

sel-9 [ER to Golgi transport vesicle membrane]

sel-9 [Golgi membrane]

sel-9 [transport vesicle]

sel-9 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

TMED2 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001370673.1

ENSEMBL

W02D7.7.1, W02D7.7.1, WBGene00004766

PRO

O17528

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