Reactome | cpz-1 [endoplasmic reticulum lumen]

cpz-1 [endoplasmic reticulum lumen]

Stable Identifier

R-CEL-5689431

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

endoplasmic reticulum lumen

Synonyms

(Glc)3(GlcNAc)2(Man)9-CTSZ, G5EGP8

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPII-mediated vesicle transport (Caenorhabditis elegans)
        
        Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        Loss of SAR1B GTPase (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        Vesicle budding (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        Cargo concentration in the ER (Caenorhabditis elegans)
        
        Inner coat assembly and cargo binding (Caenorhabditis elegans)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
        
        cpz-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EGP8

Gene Names

cpz-1

Reference Genes

BioGPS Gene:171829 cpz-1

CTD Gene:171829 cpz-1

ENSEMBL:WBGene00000788

KEGG:cel:CELE_F32B5.8 cpz-1

Monarch:171829 cpz-1

NCBI Gene:171829 cpz-1

UCSC:G5EGP8 cpz-1

Wormbase:WBGene00000788

Wormbase:WBGene00000788 cpz-1

Reference Transcript

Other Identifiers

171829

GO:0004197

GO:0005576

GO:0005615

GO:0005764

GO:0006508

GO:0008233

GO:0008234

GO:0009792

GO:0016787

GO:0016807

GO:0030312

GO:0031012

GO:0035262

GO:0040025

GO:0040032

GO:0042395

GO:0042718

GO:0048856

GO:0051603

GO:0060102

Participates

as an input of

LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)

as a component of

LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Other forms of this molecule

cpz-1 [Golgi lumen]

cpz-1 [lysosomal lumen]

cpz-1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

cpz-1 [COPII-coated ER to Golgi transport vesicle]

cpz-1 [specific granule lumen]

cpz-1 [extracellular region]

cpz-1 [ficolin-1-rich granule lumen]

Inferred From

glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)

(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

RefSeq

NP_491023.2, NP_001364831.1

ENSEMBL

WBGene00000788, F32B5.8a.1, F32B5.8a.1

IntEnz

3.4.18.1

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