Reactome | mbd-2 [nucleoplasm]

mbd-2 [nucleoplasm]

Stable Identifier

R-CEL-4657010

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

MBD3, G5ECR1

Locations in the PathwayBrowser

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Chromatin organization (Caenorhabditis elegans)

- ATP-dependent chromatin remodelers (Caenorhabditis elegans)
  - CHD chromatin remodelers (Caenorhabditis elegans)
    - CHD3, CHD4, CHD5 subfamily (Caenorhabditis elegans)
      - NuRD complex assembly (Caenorhabditis elegans)
        
        MBD3L2 binds MBD3 NuRD core complex (Caenorhabditis elegans)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
        
        mbd-2 [nucleoplasm] (Caenorhabditis elegans)
        
        MBD3L2:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
        
        mbd-2 [nucleoplasm] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Intracellular signaling by second messengers (Caenorhabditis elegans)
  - PIP3 activates AKT signaling (Caenorhabditis elegans)
    - PTEN Regulation (Caenorhabditis elegans)
      - Regulation of PTEN gene transcription (Caenorhabditis elegans)
        
        SALL4 recruits NuRD to PTEN gene (Caenorhabditis elegans)
        
        NuRD complex [nucleoplasm] (Caenorhabditis elegans)
        
        mbd-2 [nucleoplasm] (Caenorhabditis elegans)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Caenorhabditis elegans)
        
        SALL4:NuRD [nucleoplasm] (Caenorhabditis elegans)
        
        NuRD complex [nucleoplasm] (Caenorhabditis elegans)
        
        mbd-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5ECR1

Gene Names

mbd-2

Reference Genes

BioGPS Gene:3565704 mbd-2

ENSEMBL:WBGene00023409

KEGG:cel:CELE_C27A12.10 mbd-2

Monarch:3565704 mbd-2

NCBI Gene:3565704 mbd-2

UCSC:G5ECR1 mbd-2

Wormbase:WBGene00023409

Wormbase:WBGene00023409 mbd-2

Reference Transcript

RefSeq:NM_001025841.4 mbd-2

Other Identifiers

3565704

GO:0000122

GO:0005634

GO:0006325

GO:0006346

GO:0006355

GO:0008327

Participates

as a component of

Other forms of this molecule

mbd-2 [nucleoplasm]

Inferred From

MBD3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001021012.1

ENSEMBL

WBGene00023409, C27A12.10.1, C27A12.10.1

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