Reactome | CETN2 [nucleoplasm]

CETN2 [nucleoplasm]

Stable Identifier

R-CEL-4570490

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

P30644

Locations in the PathwayBrowser

Expand all

DNA Repair (Caenorhabditis elegans)

- Nucleotide Excision Repair (Caenorhabditis elegans)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Caenorhabditis elegans)
    - DNA Damage Recognition in GG-NER (Caenorhabditis elegans)
      - PARP1 or PARP2 PARylates DDB2 and autoPARylates (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - UV-DDB ubiquitinates XPC (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - XPC binds RAD23 and CETN2 (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
    - Formation of Incision Complex in GG-NER (Caenorhabditis elegans)
      - ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - Recruitment of XPA and release of CAK (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - SUMOylation of XPC (Caenorhabditis elegans)
        
        Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub,SUMO:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
      - TFIIH binds GG-NER site to form a verification complex (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB [nucleoplasm] (Caenorhabditis elegans)
        
        Ub:XPC:RAD23:CETN2 [nucleoplasm] (Caenorhabditis elegans)
        
        CETN2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P30644

Reference Genes

BioGPS Gene:187699

CTD Gene:187699

ENSEMBL:WBGene00011145

KEGG:cel:CELE_R08D7.5

Monarch:187699

NCBI Gene:187699

UCSC:P30644

Wormbase:WBGene00011145

Reference Transcript

RefSeq:NM_066585.3

Participates

as a component of

as an input of

XPC binds RAD23 and CETN2 (Caenorhabditis elegans)

Other forms of this molecule

Misfolded CETN1 [cytosol]

Ub-Misfolded CETN1 [cytosol]

PolyUb-Misfolded CETN1 [cytosol]

Inferred From

CETN2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_498986.3

PRO

P30644

Cite Us!