Reactome | dlc-1 [cytosol]

dlc-1 [cytosol]

Stable Identifier

R-CEL-387105

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

DYNLL1, Q22799

Locations in the PathwayBrowser

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Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPI-mediated anterograde transport (Caenorhabditis elegans)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPI-mediated anterograde transport (Caenorhabditis elegans)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Dynein complex [cytosol] (Caenorhabditis elegans)
        
        dlc-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q22799

Gene Names

dlc-1

Reference Genes

BioGPS Gene:175922 dlc-1

CTD Gene:175922 dlc-1

ENSEMBL:WBGene00001005

KEGG:cel:CELE_T26A5.9 dlc-1

Monarch:175922 dlc-1

NCBI Gene:175922 dlc-1

UCSC:Q22799 dlc-1

Wormbase:WBGene00001005

Wormbase:WBGene00001005 dlc-1

Reference Transcript

RefSeq:NM_001392125.1 dlc-1

Other Identifiers

175922

GO:0005515

GO:0005634

GO:0005635

GO:0005737

GO:0005856

GO:0005868

GO:0005874

GO:0005875

GO:0006915

GO:0007017

GO:0007018

GO:0015630

GO:0022414

GO:0030286

GO:0030473

GO:0045505

GO:0051301

GO:0051321

Participates

as a component of

Other forms of this molecule

dlc-1 [ciliary tip]

dlc-1 [cilium]

dlc-1 [ficolin-1-rich granule membrane]

dlc-1 [tertiary granule membrane]

dlc-1 [plasma membrane]

Inferred From

DLCs [cytosol] (Homo sapiens)

DYNLL1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001379626.1

ENSEMBL

T26A5.9.1, T26A5.9.1, WBGene00001005

PRO

Q22799

PDB

7Y8W