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lin-53 [nucleoplasm]
Stable Identifier
R-CEL-212223
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
nucleoplasm
Synonyms
RBBP4, P90916
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G1 phase and G1/S transition (Caenorhabditis elegans)
G0 and Early G1 (Caenorhabditis elegans)
Phosphorylation of LIN52 component of MuvB by DYRK1A (Caenorhabditis elegans)
MuvB complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
p-MuvB complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
p130 (RBL2) associates with MuvB to form DREAM complex (Caenorhabditis elegans)
DREAM complex [nucleoplasm] (Caenorhabditis elegans)
p-MuvB complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
p-MuvB complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Chromatin organization (Caenorhabditis elegans)
ATP-dependent chromatin remodelers (Caenorhabditis elegans)
CHD chromatin remodelers (Caenorhabditis elegans)
CHD3, CHD4, CHD5 subfamily (Caenorhabditis elegans)
NuRD complex assembly (Caenorhabditis elegans)
CHD and CDK2AP subunits are recruited to NuRD (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
NuRD [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
HDAC1, 2 bind MTA1, 2, 3 and RBBP4,7 (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Interaction of NuRD complexes with transcription factors (Caenorhabditis elegans)
NuRD binds Ikaros family member proteins (Caenorhabditis elegans)
IKZF1,IKZF2,IKZF3:NuRD [nucleoplasm] (Caenorhabditis elegans)
NuRD [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
NuRD [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
NuRD deacetylates telomeric nucleosomes (Caenorhabditis elegans)
NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Caenorhabditis elegans)
NuRD [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
NR2C2,NR2F2:ZNF827:NuRD:telomeric chromatin [nucleoplasm] (Caenorhabditis elegans)
NuRD [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
MBD3L1 binds MBD2 NuRD core complex (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
MBD3L1:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD2:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
MBD3L2 binds MBD3 NuRD core complex (Caenorhabditis elegans)
HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
MBD3L2:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,BBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Caenorhabditis elegans)
HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Chromatin modifying enzymes (Caenorhabditis elegans)
HATs acetylate histones (Caenorhabditis elegans)
Type B histone acetlytransferase complex acetylates histone H4 (Caenorhabditis elegans)
HAT1:RBBP7 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
RMTs methylate histone arginines (Caenorhabditis elegans)
RBBP7 binds histone H3 (Caenorhabditis elegans)
RBBP7:Replicative histone H3 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by E2F6 (Caenorhabditis elegans)
E2F6:TFDP1:EPC1 binds the PRC2 complex (Caenorhabditis elegans)
E2F6:TFDP1:EPC1:PRC2 (EZH2) core [nucleoplasm] (Caenorhabditis elegans)
PRC2 (EZH2) Core [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
PRC2 (EZH2) Core [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Neddylation (Caenorhabditis elegans)
CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Caenorhabditis elegans)
CRL4 E3 ubiquitin ligase:CAND1 [nucleoplasm] (Caenorhabditis elegans)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Caenorhabditis elegans)
DCAF protein [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Caenorhabditis elegans)
DCAF protein [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Caenorhabditis elegans)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Caenorhabditis elegans)
RBX1:CUL4:DDB1:DCAFs [nucleoplasm] (Caenorhabditis elegans)
DCAF protein [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Caenorhabditis elegans)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Caenorhabditis elegans)
DCAF protein [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Caenorhabditis elegans)
MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Caenorhabditis elegans)
MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Caenorhabditis elegans)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Caenorhabditis elegans)
PRC2 (EZH2) Core [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Caenorhabditis elegans)
PRC2 (EZH2) Core [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
SALL4 recruits NuRD to PTEN gene (Caenorhabditis elegans)
NuRD complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
SALL4:NuRD:PTEN gene [nucleoplasm] (Caenorhabditis elegans)
SALL4:NuRD [nucleoplasm] (Caenorhabditis elegans)
NuRD complex [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
lin-53 [nucleoplasm] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P90916
Gene Names
lin-53
Reference Genes
BioGPS Gene:172802 lin-53
ENSEMBL:WBGene00003036
KEGG:cel:CELE_K07A1.12 lin-53
Monarch:172802 lin-53
NCBI Gene:172802 lin-53
UCSC:P90916 lin-53
Wormbase:WBGene00003036
Wormbase:WBGene00003036 lin-53
Reference Transcript
RefSeq:NM_060151.9 lin-53
Other Identifiers
172802
GO:0000775
GO:0001708
GO:0005515
GO:0005634
GO:0005694
GO:0006325
GO:0006338
GO:0006355
GO:0009792
GO:0016581
GO:0017053
GO:0034514
GO:0035098
GO:0040027
GO:0042393
GO:0042826
GO:0045138
GO:0045892
GO:0048557
GO:0048856
GO:0070176
Participates
as a member of
DCAF protein [nucleoplasm] (Caenorhabditis elegans)
RBBP4,7 [nucleoplasm] (Caenorhabditis elegans)
Homologues of RBBP4 [nucleoplasm] (Caenorhabditis elegans)
as a component of
HAT1:RBBP7 [nucleoplasm] (Caenorhabditis elegans)
RBBP7:Replicative histone H3 [nucleoplasm] (Caenorhabditis elegans)
NuRD complex [nucleoplasm] (Caenorhabditis elegans)
as an input of
RBBP7 binds histone H3 (Caenorhabditis elegans)
Inferred From
RBBP7 [nucleoplasm]
(Homo sapiens)
RBBP4 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_492552.1
ENSEMBL
K07A1.12.1
,
K07A1.12.1
,
WBGene00003036
PRO
P90916
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q23482
1
lin-37 [nucleoplasm]
(R-CEL-389101)
0.621
5
UniProt:Q21484
1
hat-1 [nucleoplasm]
(R-CEL-3662337)
0.553
2
UniProt:O61907
3
lin-40 [nucleoplasm]
(R-CEL-3465550)
lin-40 [nucleoplasm]
(R-CEL-4657009)
lin-40 [nucleoplasm]
(R-CEL-4657013)
0.553
2
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