Reactome | FGD1 [cytosol]

FGD1 [cytosol]

Stable Identifier

R-CEL-194935-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

X5LX76

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Death Receptor Signaling (Caenorhabditis elegans)
  - p75 NTR receptor-mediated signalling (Caenorhabditis elegans)
    - Cell death signalling via NRAGE, NRIF and NADE (Caenorhabditis elegans)
      - NRAGE signals death through JNK (Caenorhabditis elegans)
        
        p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)
        
        GEFs [cytosol] (Caenorhabditis elegans)
        
        Homologues of FGD1 [cytosol] (Caenorhabditis elegans)
        
        FGD1 [cytosol] (Caenorhabditis elegans)
- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (12/13) signalling events (Caenorhabditis elegans)
      - GEFs activate RhoA,B,C (Caenorhabditis elegans)
        
        GEFs [cytosol] (Caenorhabditis elegans)
        
        Homologues of FGD1 [cytosol] (Caenorhabditis elegans)
        
        FGD1 [cytosol] (Caenorhabditis elegans)
- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
  - Signaling by Rho GTPases (Caenorhabditis elegans)
    - RHO GTPase cycle (Caenorhabditis elegans)
      - CDC42 GTPase cycle (Caenorhabditis elegans)
        
        CDC42 GEFs activate CDC42 (Caenorhabditis elegans)
        
        CDC42 GEFs [cytosol] (Caenorhabditis elegans)
        
        Homologues of FGD1 [cytosol] (Caenorhabditis elegans)
        
        FGD1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:X5LX76

Reference Genes

BioGPS Gene:177656

ENSEMBL:WBGene00006450

KEGG:cel:CELE_C28C12.10

Monarch:177656

NCBI Gene:177656

UCSC:X5LX76

Wormbase:WBGene00006450

Reference Transcript

Other Identifiers

177656

GO:0005085

GO:0005737

GO:0005856

GO:0007010

GO:0008270

GO:0046847

GO:0046872

Participates

as a member of

Homologues of FGD1 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

FGD4 [cytosol]

FGD3 [cytosol]

Inferred From

FGD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001368457.1, NP_001368458.1, NP_001294044.2, NP_501455.2, NP_001294045.1, NP_001294046.1

ENSEMBL

C28C12.10b.1, C28C12.10b.1, WBGene00006450

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