Reactome | TUBB2A [cytosol]

TUBB2A [cytosol]

Stable Identifier

R-CEL-191699

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

P12456

Locations in the PathwayBrowser

Expand all

Hemostasis (Caenorhabditis elegans)

- Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
  - Kinesins (Caenorhabditis elegans)
    - Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
      - Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPI-mediated anterograde transport (Caenorhabditis elegans)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPI-mediated anterograde transport (Caenorhabditis elegans)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
      - COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin [cytosol] (Caenorhabditis elegans)
        
        TUBB2A [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P12456

Reference Genes

BioGPS Gene:181036

ENSEMBL:WBGene00003171

Monarch:181036

NCBI Gene:181036

UCSC:P12456

Wormbase:WBGene00003171

Reference Transcript

RefSeq:NM_076912.3

Other Identifiers

171793_x_at

181036

18633928

191320_s_at

A_12_P115480

CE15257

CE_WBGene00003171_A

CGZ0056460

GO:0003824

GO:0003924

GO:0005198

GO:0005200

GO:0005525

GO:0005856

GO:0005874

GO:0007010

GO:0007017

GO:0016787

GO:0043226

WBGene00003171

ZK154.3

ZK154.3_1053-1112_0.929_19_A

ZK154_3P00070

ZK154_3P00802

ZK154_3P00820

cea2.3.31320

cea2.p.157343

Participates

as a candidate of

beta-tubulin [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

TUBB2A [axonemal microtubule]

TUBB1 [axonemal microtubule]

TUBB8 [cytosol]

TUBB1 [cytosol]

Inferred From

TUBB2B [cytosol] (Homo sapiens)

TUBB2A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_509313.1

PRO

P12456

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