Reactome | GNA11 [plasma membrane]

GNA11 [plasma membrane]

Stable Identifier

R-CEL-167446

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

G5EGU1

Locations in the PathwayBrowser

Expand all

Hemostasis (Caenorhabditis elegans)

- Platelet activation, signaling and aggregation (Caenorhabditis elegans)
  - Signal amplification (Caenorhabditis elegans)
    - ADP signalling through P2Y purinoceptor 1 (Caenorhabditis elegans)
      - P2Y purinoceptor 1 activates MAP kinase p38 alpha (Caenorhabditis elegans)
        
        G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
    - Thromboxane signalling through TP receptor (Caenorhabditis elegans)
      - Gq activation by TP receptor (Caenorhabditis elegans)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
        
        G protein-GTP [plasma membrane] (Caenorhabditis elegans)
        
        G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
  - Thrombin signalling through proteinase activated receptors (PARs) (Caenorhabditis elegans)
    - Thrombin-activated PARs activate Gq (Caenorhabditis elegans)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Caenorhabditis elegans)
        
        G protein-GTP [plasma membrane] (Caenorhabditis elegans)
        
        G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
    - Thrombin-activated PARs binds G-protein Gq (Caenorhabditis elegans)
      - Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11):GDP [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
    - Thrombin-activated PARs:Gq (active) dissociate (Caenorhabditis elegans)
      - G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Caenorhabditis elegans)
        
        G protein-GTP [plasma membrane] (Caenorhabditis elegans)
        
        G protein alpha:GTP complex [plasma membrane] (Caenorhabditis elegans)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)
        
        GNA11 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EGU1

Reference Genes

BioGPS Gene:171751

CTD Gene:171751

ENSEMBL:WBGene00001196

Monarch:171751

NCBI Gene:171751

UCSC:G5EGU1

Wormbase:WBGene00001196

Reference Transcript

RefSeq:NM_170806.6

Other Identifiers

171751

GO:0000166

GO:0001664

GO:0002119

GO:0002253

GO:0002376

GO:0003924

GO:0005525

GO:0005737

GO:0005834

GO:0005886

GO:0005938

GO:0007165

GO:0007186

GO:0007188

GO:0007210

GO:0007212

GO:0007631

GO:0007635

GO:0014057

GO:0016787

GO:0019001

GO:0030424

GO:0031683

GO:0040017

GO:0042307

GO:0043005

GO:0043025

GO:0043051

GO:0046662

GO:0046872

GO:0048680

GO:0048856

GO:0050830

GO:0050920

GO:0060158

GO:0098542

GO:1902074

GO:1902474

GO:2000292

Participates

as a candidate of

G(q) alpha 11,14,15,Q [plasma membrane] (Caenorhabditis elegans)

as a member of

G-protein alpha (q/11/14/15) [plasma membrane] (Caenorhabditis elegans)

This entity regulates

Positively

Other forms of this molecule

GNA14 [plasma membrane]

Inferred From

G-protein alpha (q/11) [plasma membrane] (Homo sapiens)

GNA11 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_740789.1

ENSEMBL

WBGene00001196, M01D7.7a.1, M01D7.7a.1

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