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K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane]
Stable Identifier
R-BTA-975172
Type
Complex
Species
Bos taurus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Bos taurus)
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Bos taurus)
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Bos taurus)
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Bos taurus)
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
(Bos taurus)
TRAF6 [endosome membrane]
(Bos taurus)
Participates
as an input of
NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Bos taurus)
as a component of
TRAF6:K63-linked polyUb p-IRAK1:IKK complex [endosome membrane] (Bos taurus)
Inferred From
K63-linked poly-Ub-p-3S,3T-IRAK1:TRAF6 [endosome membrane]
(Homo sapiens)
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