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phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
Stable Identifier
R-BTA-975157
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
endosome membrane
Synonyms
Q2LGB3
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Bos taurus)
p-Pellino:hp-IRAK1:TRAF6 [endosome membrane] (Bos taurus)
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q2LGB3
Reference Genes
BioGPS Gene:533953
ENSEMBL:ENSBTAG00000016085
KEGG:bta:533953
Monarch:533953
NCBI Gene:533953
UCSC:Q2LGB3
Reference Transcript
RefSeq:NM_001040555.1
Participates
as a component of
TRAF6:hp-IRAK1 [endosome membrane] (Bos taurus)
Other forms of this molecule
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
phospho-p-S,T-IRAK1 [cytosol]
phospho-p-S376,T387-IRAK1 [cytosol]
phospho-K63polyUb-hp-IRAK1 [cytosol]
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
IRAK1 [cytosol]
Inferred From
p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 387 (in Homo sapiens)
Coordinate
387
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 376 (in Homo sapiens)
Coordinate
376
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 209 (in Homo sapiens)
Coordinate
209
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001035645.1
VGNC
30264
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