Reactome | ATP6V0B [lysosomal membrane]

ATP6V0B [lysosomal membrane]

Stable Identifier

R-BTA-9640187

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

lysosomal membrane

Synonyms

ATP6V0B, Q2TA24

Locations in the PathwayBrowser

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Cellular responses to stimuli (Bos taurus)

- Cellular responses to stress (Bos taurus)
  - Cellular response to starvation (Bos taurus)
    - Amino acids regulate mTORC1 (Bos taurus)
      - RRAGA,B exchanges GDP for GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - RRAGA,B hydrolyzes GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - RRAGC,D exchanges GTP for GDP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - RRAGC,D hydrolyzes GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - mTORC1 binds RHEB:GTP (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Bos taurus)
        
        v-ATPase [lysosomal membrane] (Bos taurus)
        
        ATP6V0 [lysosomal membrane] (Bos taurus)
        
        ATP6V0B [lysosomal membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q2TA24

Gene Names

ATP6V0B

Reference Genes

BioGPS Gene:505684 ATP6V0B

ENSEMBL:ENSBTAG00000018889

KEGG:bta:505684 ATP6V0B

Monarch:505684 ATP6V0B

NCBI Gene:505684 ATP6V0B

UCSC:Q2TA24 ATP6V0B

Reference Transcript

RefSeq:NM_001038038.2 ATP6V0B

Other Identifiers

505684

Bt.4227.1.S1_at

GO:0005768

GO:0015078

GO:0016020

GO:0033176

GO:0033177

GO:0033179

GO:0046961

GO:0055085

GO:1902600

Participates

as a component of

ATP6V0 [lysosomal membrane] (Bos taurus)

Other forms of this molecule

ATP6V0B [phagocytic vesicle membrane]

ATP6V0B [endosome membrane]

Inferred From

ATP6V0B [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_001033127.1

ENSEMBL

ENSBTAG00000018889, ENSBTAT00000025144, ENSBTAP00000025144

VGNC

26310

PDB

6XBY, 6XBW, 7KHR

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