Reactome | phospho-CASP9 [cytosol]

phospho-CASP9 [cytosol]

Stable Identifier

R-BTA-9627087

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

p-T412-CASP9(1-416), E1BNU2

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Bos taurus)

- Apoptosis (Bos taurus)
  - Intrinsic Pathway for Apoptosis (Bos taurus)
    - Apoptotic factor-mediated response (Bos taurus)
      - Cytochrome c-mediated apoptotic response (Bos taurus)
        
        Formation of apoptosome (Bos taurus)
        
        Regulation of the apoptosome activity (Bos taurus)
        
        CASP9 is phosphorylated at T412 (Bos taurus)
        
        APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Bos taurus)
        
        phospho-CASP9 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BNU2

Gene Names

CASP9

Reference Genes

ENSEMBL:ENSBTAG00000002472.6

Other Identifiers

100140945

GO:0003824

GO:0004197

GO:0005737

GO:0006508

GO:0008233

GO:0008234

GO:0008630

GO:0012501

GO:0016787

GO:0023052

GO:0042981

GO:0097199

GO:0140096

Participates

as a component of

APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Bos taurus)

Other forms of this molecule

CASP9 [cytosol]

phospho-CASP9 [cytosol]

CASP9 [cytosol]

Inferred From

p-T412-CASP9(1-416) [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 412 (in Homo sapiens)

Coordinate

412

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

OpenTargets

ENSG00000132906

Ensembl

ENSBTAP00000003205, ENSBTAG00000002472, ENSBTAT00000003205

VGNC

106670

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