Reactome | phospho-p-T200-CAMK4 [nucleoplasm]

phospho-p-T200-CAMK4 [nucleoplasm]

Stable Identifier

R-BTA-9619155

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

A0A3Q1M5T5

Locations in the PathwayBrowser

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Neuronal System (Bos taurus)

- Transmission across Chemical Synapses (Bos taurus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
    - Activation of NMDA receptors and postsynaptic events (Bos taurus)
      - Post NMDA receptor activation events (Bos taurus)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Bos taurus)

Signal Transduction (Bos taurus)

- Intracellular signaling by second messengers (Bos taurus)
  - DAG and IP3 signaling (Bos taurus)
    - CaM pathway (Bos taurus)
      - Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Bos taurus)
- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Opioid Signalling (Bos taurus)
        
        G-protein mediated events (Bos taurus)
        
        PLC beta mediated events (Bos taurus)
        
        Ca-dependent events (Bos taurus)
        
        CaM pathway (Bos taurus)
        
        Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CAMK4 autophosphorylates (Bos taurus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1M5T5

Reference Genes

BioGPS Gene:100337083

ENSEMBL:ENSBTAG00000035662.2

KEGG:bta:100337083

Monarch:100337083

NCBI Gene:100337083

UCSC:A0A3Q1M5T5

Reference Transcript

RefSeq:XM_002691014.7

Other Identifiers

100337083

GO:0001650

GO:0002376

GO:0003824

GO:0004672

GO:0004683

GO:0005524

GO:0005654

GO:0005783

GO:0006355

GO:0006468

GO:0007616

GO:0016740

GO:0030154

GO:0043011

GO:0045893

GO:0050877

GO:0140096

Participates

as a component of

p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)

Other forms of this molecule

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm]

Inferred From

p-T200-CAMK4 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 200 (in Homo sapiens)

Coordinate

200

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_002691060.1

ENSEMBL

ENSBTAP00000065683, ENSBTAT00000086155, ENSBTAG00000035662

VGNC

106668

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