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ISG15 [cytosol]
Stable Identifier
R-BTA-936552
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
ISG15, O02741
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
ISG15 antiviral mechanism (Bos taurus)
Activation of ISG15 by UBA7 E1 ligase (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISG15:UBA7 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Competitive inhibition of translation initiation by ISGylated 4EHP (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated 4EHP:mRNA [cytosol] (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of E2 conjugating enzymes (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated E2 conjugating enzymes [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of IRF3 (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated IRF3 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of host protein filamin B (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated Filamin B [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of host proteins (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated host proteins [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated PP2CB [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylation of protein translation regulator 4EHP (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated 4EHP [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Interaction of E3 ligase with ISG15:E2 complex (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISG15:NEDD4 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Bos taurus)
ISGylated host proteins [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Transfer of ISG15 from E1 to E2 (UBCH8) (Bos taurus)
ISG15:UBA7 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
PKR-mediated signaling (Bos taurus)
ISGylation of PKR (Bos taurus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Modulation of host responses by IFN-stimulated genes (Bos taurus)
ISGylation of DDX58 (RIG-I) (Bos taurus)
ISG15:UBA7 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISGylated DDX58 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
Negative regulators of DDX58/IFIH1 signaling (Bos taurus)
ISGylation of DDX58 (Bos taurus)
ISG15:DDX58 conjugate [cytosol] (Bos taurus)
ISG15:UBEIL/UbcH8:CEB1 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
ISG15:UBEIL/UbcH8:CEB1 [cytosol] (Bos taurus)
ISG15 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:O02741
Gene Names
ISG15
Reference Genes
BioGPS Gene:281871 ISG15
ENSEMBL:ENSBTAG00000014707
KEGG:bta:281871 ISG15
Monarch:281871 ISG15
NCBI Gene:281871 ISG15
UCSC:O02741 ISG15
Reference Transcript
RefSeq:NM_174366.1 ISG15
Other Identifiers
281871
GO:0002376
GO:0005178
GO:0005576
GO:0007229
GO:0009615
GO:0009617
GO:0019941
GO:0030501
GO:0031386
GO:0031397
GO:0032020
GO:0032461
GO:0032649
GO:0032728
GO:0032729
GO:0032733
GO:0034340
GO:0042742
GO:0045071
GO:0045087
GO:0045648
GO:0051607
GO:0060339
GO:0070585
GO:0098542
Participates
as a component of
ISGylated DDX58 [cytosol] (Bos taurus)
ISGylated PP2CB [cytosol] (Bos taurus)
ISGylated E2 conjugating enzymes [cytosol] (Bos taurus)
ISGylated Filamin B [cytosol] (Bos taurus)
ISG15:NEDD4 [cytosol] (Bos taurus)
ISGylated host proteins [cytosol] (Bos taurus)
ISG15:UBEIL/UbcH8:CEB1 [cytosol] (Bos taurus)
ISG15:UBA7 [cytosol] (Bos taurus)
ISG15:UBCH8 [cytosol] (Bos taurus)
ISGylated IRF3 [cytosol] (Bos taurus)
as an input of
Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Bos taurus)
Activation of ISG15 by UBA7 E1 ligase (Bos taurus)
Other forms of this molecule
ISG15 [nucleoplasm]
ISG15 [nucleoplasm]
Inferred From
ISG15 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_776791.1
ENSEMBL
ENSBTAT00000019573
,
ENSBTAP00000019573
VGNC
30293
PDB
6JH1
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