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TRAF3 [cytosol]
Stable Identifier
R-BTA-914241
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
TRAF3, E1BBH2
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
TNFR2 non-canonical NF-kB pathway (Bos taurus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Bos taurus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Bos taurus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Bos taurus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Bos taurus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF2:cIAP1/2 complex binds FN14:TWEAK (Bos taurus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3 binds BAFFR:BAFF (Bos taurus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAFs bind RANK:RANKL (Bos taurus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Bos taurus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Bos taurus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Bos taurus)
TNFSF:TNFRSF heterotrimer:K63polyUb-cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Bos taurus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Bos taurus)
Auto-ubiquitination of TRAF3 (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3 binds TICAM1:activated TLR4 complex (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Deubiquitination (Bos taurus)
Ovarian tumor domain proteases (Bos taurus)
OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Bos taurus)
OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Bos taurus)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Bos taurus)
TRAF3 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BBH2
Gene Names
TRAF3
Reference Genes
BioGPS Gene:506182 TRAF3
ENSEMBL:ENSBTAG00000013475.5
KEGG:bta:506182 TRAF3
Monarch:506182 TRAF3
NCBI Gene:506182 TRAF3
UCSC:E1BBH2 TRAF3
Reference Transcript
RefSeq:XM_024981638.2 TRAF3
RefSeq:NM_001205586.2 TRAF3
Other Identifiers
506182
Bt.18290.1.A1_at
Bt.18290.2.S1_at
GO:0001817
GO:0002224
GO:0002376
GO:0003824
GO:0004842
GO:0005164
GO:0005515
GO:0005739
GO:0005768
GO:0006355
GO:0007165
GO:0008063
GO:0008270
GO:0009898
GO:0010008
GO:0016740
GO:0019901
GO:0019903
GO:0030162
GO:0031625
GO:0031996
GO:0032088
GO:0032481
GO:0032648
GO:0033209
GO:0034142
GO:0035631
GO:0042802
GO:0042981
GO:0045087
GO:0050688
GO:0061630
GO:0098542
GO:0140096
Participates
as a member of
RNF128,TRAF3,TRAF6,RHOA,TP53 [cytosol] (Bos taurus)
as an output of
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Bos taurus)
as a component of
TRAF3:NIK [cytosol] (Bos taurus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
as an input of
TRAF3 binds TICAM1:activated TLR4 complex (Bos taurus)
Other forms of this molecule
TRAF3 [cytosol]
TRAF3 [cytosol]
Inferred From
TRAF3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_024837406.1
,
NP_001192515.1
ENSEMBL
ENSBTAT00000086260
,
ENSBTAP00000067220
,
ENSBTAG00000069778
VGNC
36272
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