Reactome | AVP [clathrin-coated endocytic vesicle membrane]

AVP [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-BTA-8869075

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

AVP(20-28), A0A3Q1LXY0

Locations in the PathwayBrowser

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Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - Clathrin-mediated endocytosis (Bos taurus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Bos taurus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Bos taurus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)
    - RAB5 and GAPVD1 bind AP-2 (Bos taurus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB:ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        ARRB-binding GPCRs [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)
        
        AVP [clathrin-coated endocytic vesicle membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1LXY0

Gene Names

AVP

Reference Genes

ENSEMBL:ENSBTAG00000008027.5

UCSC:A0A3Q1LXY0 AVP

Other Identifiers

280728

Bt.184.1.S1_at

GO:0005185

GO:0005576

GO:0048018

GO:0098772

Participates

as a component of

AVPR2:AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Bos taurus)

Other forms of this molecule

AVP [cytosol]

AVP [extracellular region]

Inferred From

AVP(20-28) [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSBTAG00000008027, ENSBTAP00000062113, ENSBTAT00000076190

VGNC

26356

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