Reactome | ARFGAP3 [cytosol]

ARFGAP3 [cytosol]

Stable Identifier

R-BTA-6807740

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

ARFGAP3, Q17R07

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Transport to the Golgi and subsequent modification (Bos taurus)
      - ER to Golgi Anterograde Transport (Bos taurus)
        
        COPI-mediated anterograde transport (Bos taurus)
        
        ARFGAPs stimulate ARF GTPase activity (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)

Signal Transduction (Bos taurus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
  - Signaling by Rho GTPases (Bos taurus)
    - RHO GTPase cycle (Bos taurus)
      - RHOG GTPase cycle (Bos taurus)
        
        RHOG binds effectors at the plasma membrane (Bos taurus)
        
        RHOG plasma membrane effectors [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Bos taurus)
        
        RHOG plasma membrane effectors [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)

Vesicle-mediated transport (Bos taurus)

- Membrane Trafficking (Bos taurus)
  - ER to Golgi Anterograde Transport (Bos taurus)
    - COPI-mediated anterograde transport (Bos taurus)
      - ARFGAPs stimulate ARF GTPase activity (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
    - Golgi-to-ER retrograde transport (Bos taurus)
      - COPI-dependent Golgi-to-ER retrograde traffic (Bos taurus)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q17R07

Gene Names

ARFGAP3

Reference Genes

BioGPS Gene:532778 ARFGAP3

ENSEMBL:ENSBTAG00000001057

KEGG:bta:532778 ARFGAP3

Monarch:532778 ARFGAP3

NCBI Gene:532778 ARFGAP3

UCSC:Q17R07 ARFGAP3

Reference Transcript

RefSeq:NM_001075974.1 ARFGAP3

Other Identifiers

532778

Bt.6257.1.S1_at

Bt.7439.1.S1_at

GO:0005096

GO:0005794

GO:0005829

GO:0009306

GO:0098772

Participates

as a candidate of

as a member of

ARFGAP1,2,3 [cytosol] (Bos taurus)

Inferred From

ARFGAP3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001069442.1

ENSEMBL

ENSBTAG00000001057, ENSBTAT00000053995, ENSBTAP00000050747

VGNC

26063

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