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PolyUb-TP53 [nucleoplasm]
Stable Identifier
R-BTA-6793679
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
P67939
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G1/S DNA Damage Checkpoints (Bos taurus)
p53-Dependent G1/S DNA damage checkpoint (Bos taurus)
p53-Dependent G1 DNA Damage Response (Bos taurus)
Stabilization of p53 (Bos taurus)
Ubiquitinated TP53 translocates to the cytosol (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
G2/M Checkpoints (Bos taurus)
GTSE1 binds TP53 (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
GTSE1 promotes translocation of TP53 to the cytosol (Bos taurus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds TP53 (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
GTSE1 promotes translocation of TP53 to the cytosol (Bos taurus)
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Expression and Degradation (Bos taurus)
Regulation of TP53 Degradation (Bos taurus)
USP7 deubiquitinates TP53 and counteracts MDM2 (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
Ubiquitinated TP53 translocates to the cytosol (Bos taurus)
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
PolyUb-TP53 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:P67939
Reference Genes
BioGPS Gene:281542
ENSEMBL:ENSBTAG00000001069
ENSEMBL:ENSBTAG00000001069.5
KEGG Gene (Bos taurus):281542
Monarch:281542
NCBI Gene:281542
Reference Transcript
RefSeq:NM_174201.2
Other Identifiers
281542
Participates
as a component of
PolyUb-TP53 Tetramer [nucleoplasm] (Bos taurus)
Other forms of this molecule
TP53 [cytosol]
PolyUb-TP53 [nucleoplasm]
polySUMO2,3-K386-TP53 [nucleoplasm]
phospho-p-S392-TP53 [nucleoplasm]
Me2K-370,382-TP53 [nucleoplasm]
phospho-p-S15,S33,S46-TP53 [nucleoplasm]
phospho-p-S15,S392-TP53 [nucleoplasm]
phospho-p-T55-TP53 [nucleoplasm]
phospho-p-S15,S20,S392-TP53 [nucleoplasm]
phospho-p-S15,S20,S269,T284-TP53 [nucleoplasm]
phospho-p-S15,S20-TP53 [nucleoplasm]
phospho-p-S15-TP53 [nucleoplasm]
TP53 [nucleoplasm]
PolyUb-TP53 [cytosol]
phospho-p-S15,S20,S46-TP53 [nucleoplasm]
phospho-Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
phospho-Ac-K382,p-S15,S20-TP53 [nucleoplasm]
phospho-Ac-K120,p-S15,S20-TP53 [nucleoplasm]
phospho-Me1-K372,p-S15,S20-TP53 [nucleoplasm]
phospho-Me-K382,p-S15,S20-TP53 [nucleoplasm]
phospho-p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
phospho-MeK-370,p-S15,S20-TP53 [nucleoplasm]
Me2-K373-TP53 [nucleoplasm]
phospho-PolyUb,p-S15,S20-TP53 [nucleoplasm]
phospho-p-S315-TP53 [nucleoplasm]
phospho-p-S37-TP53 [nucleoplasm]
Inferred From
PolyUb-TP53 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (PolyUb [nucleoplasm]) at unknown position
Modification
PolyUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_776626.1
Ensembl
ENSBTAP00000001420
,
ENSBTAG00000001069
,
ENSBTAT00000001420
VGNC
36231
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