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phospho-MDM2 [nucleoplasm]
Stable Identifier
R-BTA-6792862
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
p-S166,S188,T218-MDM2, F1MYE6
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Expression and Degradation (Bos taurus)
Regulation of TP53 Degradation (Bos taurus)
(CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Bos taurus)
phospho-MDM2 [nucleoplasm] (Bos taurus)
CCNG1 recruits PP2A-PPP2R5C to MDM2 (Bos taurus)
PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm] (Bos taurus)
phospho-MDM2 [nucleoplasm] (Bos taurus)
phospho-MDM2 [nucleoplasm] (Bos taurus)
PP2A-PP2R5C dephosphorylates MDM2 (Bos taurus)
PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm] (Bos taurus)
phospho-MDM2 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MYE6
Gene Names
MDM2
Reference Genes
ENSEMBL:ENSBTAG00000010422.6
UCSC:F1MYE6 MDM2
Other Identifiers
540378
Bt.17772.1.S1_at
GO:0000122
GO:0001568
GO:0001974
GO:0002027
GO:0002039
GO:0003170
GO:0003181
GO:0003203
GO:0003281
GO:0003283
GO:0003723
GO:0003824
GO:0004842
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006355
GO:0006511
GO:0006915
GO:0007089
GO:0007507
GO:0008097
GO:0008270
GO:0010468
GO:0016567
GO:0016604
GO:0016740
GO:0016874
GO:0017053
GO:0019899
GO:0019904
GO:0030163
GO:0030330
GO:0031625
GO:0031648
GO:0032436
GO:0032991
GO:0034451
GO:0034504
GO:0042176
GO:0042802
GO:0043021
GO:0043066
GO:0043130
GO:0043161
GO:0043518
GO:0045184
GO:0045787
GO:0045892
GO:0045931
GO:0046677
GO:0048856
GO:0051149
GO:0051603
GO:0051726
GO:0051865
GO:0060411
GO:0061630
GO:0061663
GO:0065003
GO:0071456
GO:0071480
GO:0072331
GO:0072717
GO:0097718
GO:0140096
GO:1901797
GO:1902254
GO:1990000
Participates
as an input of
CCNG1 recruits PP2A-PPP2R5C to MDM2 (Bos taurus)
as a component of
PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm] (Bos taurus)
as an output of
(CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Bos taurus)
Other forms of this molecule
MDM2 [nucleoplasm]
MDM2 [nucleoplasm]
MDM2 [plasma membrane]
MDM2 [endocytic vesicle membrane]
phospho-MDM2 [nucleoplasm]
phospho-MDM2 [nucleoplasm]
MDM2 [nucleoplasm]
MDM2 [cytosol]
phospho-MDM2 [cytosol]
phospho-MDM2 [nucleoplasm]
Inferred From
p-T218,S166,S188-MDM2, p-S166,S188-MDM2 [nucleoplasm]
(Homo sapiens)
p-S166,S188,T218-MDM2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 218 (in Homo sapiens)
Coordinate
218
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 166 (in Homo sapiens)
Coordinate
166
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 188 (in Homo sapiens)
Coordinate
188
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENSBTAT00000045265
,
ENSBTAG00000010422
,
ENSBTAP00000042668
VGNC
31336
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