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MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm]
Stable Identifier
R-BTA-6786151
Type
Complex
Species
Bos taurus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
Fanconi Anemia Pathway (Bos taurus)
DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
POLN binds ICL-DNA (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
Translesion synthesis across unhooked ICL by POLN (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
FA core complex [nucleoplasm]
(Bos taurus)
Ghost homologue of Unhooked ICL-DNA [nucleoplasm]
(Bos taurus)
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI [nucleoplasm]
(Bos taurus)
Participates
as an input of
POLN binds ICL-DNA (Bos taurus)
as a component of
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Bos taurus)
as an output of
DNA nucleases unhook the interstrand crosslink (ICL) (Bos taurus)
Inferred From
MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm]
(Homo sapiens)
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