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TCEA1 [nucleoplasm]
Stable Identifier
R-BTA-65748
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
Q29RL9
Locations in the PathwayBrowser
Expand all
DNA Repair (Bos taurus)
Nucleotide Excision Repair (Bos taurus)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Bos taurus)
Dual incision in TC-NER (Bos taurus)
3' incision by ERCC5 (XPG) in TC-NER (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Bos taurus)
TC-NER incision complex [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Bos taurus)
TC-NER incision complex [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Bos taurus)
TC-NER pre-incision complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
ERCC5 and RPA bind TC-NER site (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Formation of TC-NER Pre-Incision Complex (Bos taurus)
Assembly of the pre-incision complex in TC-NER (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
UVSSA:USP7 deubiquitinates ERCC6 (Bos taurus)
TC-NER pre-incision complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Gap-filling DNA repair synthesis and ligation in TC-NER (Bos taurus)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Transcription of DNA Repair Genes (Bos taurus)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Bos taurus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Bos taurus)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Bos taurus)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
RNA Polymerase II Pre-transcription Events (Bos taurus)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Bos taurus)
Paused processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Abortive termination of elongation after arrest (Bos taurus)
Aborted elongation complex after arrest [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Resumption of elongation after recovery from pausing (Bos taurus)
Paused processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
TFIIS-mediated recovery of elongation from arrest (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription Elongation (Bos taurus)
Addition of nucleotides leads to transcript elongation (Bos taurus)
Elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Pol II elongation complex moves on the template as transcript elongates (Bos taurus)
Elongation complex prior to separation [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Separation of elongating transcript from template (Bos taurus)
Elongation complex prior to separation [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Bos taurus)
TCEA1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:Q29RL9
Reference Genes
BioGPS Gene:505722
ENSEMBL:ENSBTAG00000003460
KEGG:bta:505722
Monarch:505722
NCBI Gene:505722
UCSC:Q29RL9
Reference Transcript
RefSeq:NM_001045925.1
Participates
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Bos taurus)
Paused processive elongation complex [nucleoplasm] (Bos taurus)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Bos taurus)
Elongation complex prior to separation [nucleoplasm] (Bos taurus)
Processive elongation complex [nucleoplasm] (Bos taurus)
Elongation complex [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Bos taurus)
TC-NER pre-incision complex [nucleoplasm] (Bos taurus)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Bos taurus)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Bos taurus)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Bos taurus)
as an input of
Assembly of the pre-incision complex in TC-NER (Bos taurus)
Inferred From
TCEA1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001039390.1
VGNC
35679
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