Reactome | PAR-PARP1,PAR-PARP2 dimers [nucleoplasm]

PAR-PARP1,PAR-PARP2 dimers [nucleoplasm]

Stable Identifier

R-BTA-5651709

Type

Complex

Species

Bos taurus

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 PAR-PARP1,PAR-PARP2 [nucleoplasm] (Bos taurus)

Participates

as an input of

PARG dePARylates PARP1,PARP2 (Bos taurus)

as an output of

PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Bos taurus)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Bos taurus)
PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Bos taurus)

as a component of

PAR-PARP1,PAR-PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Bos taurus)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Bos taurus)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Bos taurus)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Bos taurus)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Bos taurus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Bos taurus)

Inferred From

PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] (Homo sapiens)