Reactome | phospho-H3-3B [nucleoplasm]

phospho-H3-3B [nucleoplasm]

Stable Identifier

R-BTA-5625858

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

p-T12,MeK-H3F3A, Q5E9F8

Locations in the PathwayBrowser

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Signal Transduction (Bos taurus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
  - Signaling by Rho GTPases (Bos taurus)
    - RHO GTPase Effectors (Bos taurus)
      - RHO GTPases activate PKNs (Bos taurus)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Bos taurus)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        phospho-H3-3B [nucleoplasm] (Bos taurus)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
        
        phospho-H3-3B [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:Q5E9F8 H3-3A

Gene Names

H3-3A, H3F3A, H3-3B, H3F3B

Chain

initiator methionine:1, chain:2-136

Reference Genes

BioGPS Gene:326601 H3-3A

BioGPS Gene:617051 H3-3A

KEGG:bta:326601 H3-3A

KEGG:bta:617051 H3-3A

Monarch:326601 H3-3A

Monarch:617051 H3-3A

NCBI Gene:326601 H3-3A

NCBI Gene:617051 H3-3A

UCSC:Q5E9F8 H3-3A

Reference Transcript

Other Identifiers

326601

617051

Bt.15474.1.S1_at

Bt.28226.3.A1_s_at

Bt.5089.1.S1_at

Bt.5089.1.S2_at

Bt.5089.1.S3_at

Bt.5388.1.S1_at

Bt.5388.1.S1_s_at

GO:0000781

GO:0000786

GO:0000978

GO:0000979

GO:0003677

GO:0005198

GO:0005634

GO:0005654

GO:0006325

GO:0006334

GO:0030307

GO:0030527

GO:0031492

GO:0032991

GO:0046982

GO:0065003

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)

Other forms of this molecule

Me2K5-H3F3A [nucleoplasm]

H3-3B [nucleoplasm]

H3-3B [extracellular region]

Me3K5-H3F3A [nucleoplasm]

H3-3B [nucleoplasm]

phospho-H3-3B [nucleoplasm]

H3-3B [nucleoplasm]

phospho-H3-3B [nucleoplasm]

H3-3B [nucleoplasm]

Inferred From

p-T12,MeK-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001014411.1, NP_001229500.1

ENSEMBL

ENSBTAP00000034086, ENSBTAG00000024561, ENSBTAP00000034581, ENSBTAG00000024909, ENSBTAT00000034186, ENSBTAT00000034695

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