TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA

Stable Identifier
R-BTA-5432387
Type
Reaction [binding]
Species
Bos taurus
Compartment
mitochondrial matrix, mitochondrial inner membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA
The ternary complex containing TUFM:GTP (EF-Tu:GTP) and aminoacyl-tRNA enters the A-site of the 55S ribosome (Kumazawa et al. 1991, Schwartzbach and Spremulli 1991, Woriax et al. 1997, reviewed in Christian and Spremulli 2012).
Literature References
PubMed ID Title Journal Year
1932108 Interactions of bovine mitochondrial phenylalanyl-tRNA with ribosomes and elongation factors from mitochondria and bacteria

Kumazawa, Y, Schwartzbach, CJ, Liao, HX, Mizumoto, K, Kaziro, Y, Miura, K, Watanabe, K, Spremulli, LL

Biochim. Biophys. Acta 1991
9177487 Mechanistic studies of the translational elongation cycle in mammalian mitochondria

Woriax, VL, Bullard, JM, Ma, L, Yokogawa, T, Spremulli, LL

Biochim. Biophys. Acta 1997
1885567 Interaction of animal mitochondrial EF-Tu.EF-Ts with aminoacyl-tRNA, guanine nucleotides, and ribosomes

Schwartzbach, CJ, Spremulli, LL

J. Biol. Chem. 1991
22172991 Mechanism of protein biosynthesis in mammalian mitochondria

Christian, BE, Spremulli, LL

Biochim. Biophys. Acta 2012
Participants
Input
Output
Orthologous Events
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
Authored
May, B  (2014-05-09)
Reviewed
Chrzanowska-Lightowlers, ZM  (2014-08-29)
Spremulli, LL  (2014-09-20)
Created
May, B  (2014-05-11)
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