Reactome | CAMKK2 [nucleoplasm]

CAMKK2 [nucleoplasm]

Stable Identifier

R-BTA-5336483

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

CAMKK2, Q148H3

Locations in the PathwayBrowser

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Neuronal System (Bos taurus)

- Transmission across Chemical Synapses (Bos taurus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
    - Activation of NMDA receptors and postsynaptic events (Bos taurus)
      - Post NMDA receptor activation events (Bos taurus)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Bos taurus)
        
        CaMKK autophosphorylates in the nucleus (Bos taurus)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        CaMKK [nucleoplasm] (Bos taurus)
        
        CAMKK2 [nucleoplasm] (Bos taurus)

Signal Transduction (Bos taurus)

- Intracellular signaling by second messengers (Bos taurus)
  - DAG and IP3 signaling (Bos taurus)
    - CaM pathway (Bos taurus)
      - Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CaMKK autophosphorylates in the nucleus (Bos taurus)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        CaMKK [nucleoplasm] (Bos taurus)
        
        CAMKK2 [nucleoplasm] (Bos taurus)
- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (i) signalling events (Bos taurus)
      - Opioid Signalling (Bos taurus)
        
        G-protein mediated events (Bos taurus)
        
        PLC beta mediated events (Bos taurus)
        
        Ca-dependent events (Bos taurus)
        
        CaM pathway (Bos taurus)
        
        Calmodulin induced events (Bos taurus)
        
        CaMK IV-mediated phosphorylation of CREB (Bos taurus)
        
        CaMKK autophosphorylates in the nucleus (Bos taurus)
        
        CaMKK:CALM1:4xCa2+ [nucleoplasm] (Bos taurus)
        
        CaMKK [nucleoplasm] (Bos taurus)
        
        CAMKK2 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:Q148H3

Gene Names

CAMKK2

Reference Genes

BioGPS Gene:509084 CAMKK2

ENSEMBL:ENSBTAG00000010815.6

KEGG:bta:509084 CAMKK2

Monarch:509084 CAMKK2

NCBI Gene:509084 CAMKK2

UCSC:Q148H3 CAMKK2

Reference Transcript

Participates

as a member of

CaMKK [nucleoplasm] (Bos taurus)

Other forms of this molecule

CAMKK2 [cytosol]

phospho-CAMKK2 [cytosol]

phospho-CAMKK2 [nucleoplasm]

Inferred From

CAMKK2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_024832898.1, NP_001068858.1, XP_005217833.1

VGNC

26726

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