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IL2RG [plasma membrane]
Stable Identifier
R-BTA-449139
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
IL2RG, Q95118
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-2 family signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-15 signaling (Bos taurus)
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)
IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-2 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Bos taurus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated STAT5 is released (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylation of IL2RB Y338 enables SHC recruitment (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Recruited STAT5 is phosphorylated (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 bound to IL2 receptor is phosphorylated (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SYK binds IL2RB (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SYK is a substrate for JAK1 (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-21 signaling (Bos taurus)
IL21 receptor JAK phosphorylation (Bos taurus)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21 receptor STAT binding (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21 receptor STAT phosphorylation (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:JAK1 binds IL2RG:JAK3 (Bos taurus)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-9 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-4 and Interleukin-13 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2 binds IL2RG:JAK3 (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK1 binds IL4R in IL4-bound IL4R1 (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-7 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1 binds IL2RG:JAK3 (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Bos taurus)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q95118
Gene Names
IL2RG
Reference Genes
BioGPS Gene:281862 IL2RG
ENSEMBL:ENSBTAG00000007626
KEGG Gene (Bos taurus):281862 IL2RG
Monarch:281862 IL2RG
NCBI Gene:281862 IL2RG
Reference Transcript
RefSeq:NM_174359.1 IL2RG
Other Identifiers
GO:0004896
GO:0005886
GO:0009897
GO:0009986
GO:0016020
GO:0016192
GO:0019221
GO:0019955
GO:0023052
GO:0035723
GO:0042010
GO:0043235
GO:0050766
GO:0060089
Participates
as a component of
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
as an input of
IL2RG binds JAK3 (Bos taurus)
Other forms of this molecule
IL2RG [endosome]
phospho-IL2RG [cytosol]
phospho-IL2RG [plasma membrane]
Inferred From
IL2RG [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_776784.1
OpenTargets
ENSG00000147168
Ensembl
ENSBTAP00000010033
,
ENSBTAT00000010033
,
ENSBTAG00000007626
VGNC
30153
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