Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
IL2RG [plasma membrane]
Stable Identifier
R-BTA-449139
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
IL2RG, Q95118
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-2 family signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-15 signaling (Bos taurus)
IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15:IL15RA binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)
IL15:IL15RA:IL2RB:p-Y-JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-2 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Bos taurus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated STAT5 is released (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylation of IL2RB Y338 enables SHC recruitment (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Recruited STAT5 is phosphorylated (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 bound to IL2 receptor is phosphorylated (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SYK binds IL2RB (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SYK is a substrate for JAK1 (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3:p-SYK [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2:IL2R trimer:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-21 signaling (Bos taurus)
IL21 receptor JAK phosphorylation (Bos taurus)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21 receptor STAT binding (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21 receptor STAT phosphorylation (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y693-STAT4,(p-Y694-STAT5A,p-Y699-STAT5B) [plasma membrane] (Bos taurus)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL21:IL21R:JAK1 binds IL2RG:JAK3 (Bos taurus)
IL21:IL21R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-9 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9 binds IL9R:JAK1 and IL2RG:JAK3 (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)
IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y701-STAT1,p-Y705-STAT3,p-Y649-STAT5 [plasma membrane] (Bos taurus)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits GRB2:GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Phosphorylated SHC1 recruits SHIP (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-4 and Interleukin-13 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2 binds IL2RG:JAK3 (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK1 binds IL4R in IL4-bound IL4R1 (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] (Bos taurus)
IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Interleukin-7 signaling (Bos taurus)
IL2RG binds JAK3 (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1 binds IL2RG:JAK3 (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunits [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Bos taurus)
IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B [plasma membrane] (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
RAS GEFs [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Bos taurus)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] (Bos taurus)
IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
IL2RG [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q95118
Gene Names
IL2RG
Reference Genes
BioGPS Gene:281862 IL2RG
ENSEMBL:ENSBTAG00000007626
KEGG:bta:281862 IL2RG
Monarch:281862 IL2RG
NCBI Gene:281862 IL2RG
UCSC:Q95118 IL2RG
Reference Transcript
RefSeq:NM_174359.1 IL2RG
Participates
as a component of
IL2RG:p-Y-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-JAK3 [plasma membrane] (Bos taurus)
IL2RG:p-Y904,939-JAK3 [plasma membrane] (Bos taurus)
IL2RG:JAK3 [plasma membrane] (Bos taurus)
as an input of
IL2RG binds JAK3 (Bos taurus)
Other forms of this molecule
IL2RG [endosome]
phospho-IL2RG [cytosol]
phospho-IL2RG [plasma membrane]
Inferred From
IL2RG [plasma membrane]
(Homo sapiens)
Cross References
VGNC
30153
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
