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About
What is Reactome ?
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Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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TAB2,TAB3 [cytosol]
Stable Identifier
R-BTA-446874
Type
Set [DefinedSet]
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
Polyubiquitinated TRAF6 binds the TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1 is activated within the TAK1 complex (Bos taurus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1 phosphorylates MKK6 (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Interleukin-17 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
Alpha-protein kinase 1 signaling pathway (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
C-type lectin receptors (CLRs) (Bos taurus)
CLEC7A (Dectin-1) signaling (Bos taurus)
K63polyUb-TAK1 autophosphorylates (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [plasma membrane] (Bos taurus)
TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1 [plasma membrane] (Bos taurus)
TAB1:TAB2,TAB3:K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [plasma membrane] (Bos taurus)
TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1 [plasma membrane] (Bos taurus)
TAB1:TAB2,TAB3:K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated NF-kB activation (Bos taurus)
Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Phosphorylation of IKK-beta by TAK1 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Bos taurus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Bos taurus)
NOD1/2 Signaling Pathway (Bos taurus)
TAK1 is activated (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1 phosphorylates MKK6 (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Bos taurus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Phosphorylated TAK1 leaves activated TLR receptor complex (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Ubiquitination of IKBKG by TRAF6 (Bos taurus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
TNF signaling (Bos taurus)
TNFR1-induced NF-kappa-B signaling pathway (Bos taurus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
TAB2,TAB3 [cytosol] (Bos taurus)
Participants
members
TAB2 [cytosol]
(Bos taurus)
TAB3 [cytosol]
(Bos taurus)
Participates
as a component of
TAB1:TAB2,TAB3:K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] (Bos taurus)
TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1 [cytosol] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] (Bos taurus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] (Bos taurus)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Bos taurus)
TAK1 complex [cytosol] (Bos taurus)
Inferred From
TAB2,TAB3 [cytosol]
(Homo sapiens)
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