Reactome | phospho-p-T287-CAMK2D [cytosol]

phospho-p-T287-CAMK2D [cytosol]

Stable Identifier

R-BTA-445370

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

Q2HJF7

Locations in the PathwayBrowser

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Immune System (Bos taurus)

- Cytokine Signaling in Immune system (Bos taurus)
  - Interferon Signaling (Bos taurus)
    - Interferon gamma signaling (Bos taurus)
      - Phosphorylation of STAT1 at Ser727 (Bos taurus)
        
        CaMKII and PKC-delta [cytosol] (Bos taurus)
        
        CaMKII [cytosol] (Bos taurus)
        
        CaMKII delta/gamma [cytosol] (Bos taurus)
        
        phospho-p-T287-CAMK2D [cytosol] (Bos taurus)

Neuronal System (Bos taurus)

- Transmission across Chemical Synapses (Bos taurus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
    - Activation of NMDA receptors and postsynaptic events (Bos taurus)
      - Unblocking of NMDA receptors, glutamate binding and activation (Bos taurus)
        
        Membrane depolarization upon activation of Ca impermeable AMPA receptors (Bos taurus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Bos taurus)
        
        p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Bos taurus)
        
        p-T286-CaMKII dodecamer [cytosol] (Bos taurus)
        
        p-T286-CAMK2A,p-T287-CAMK2B,(p-T287-CAMK2D,p-T287-CAMK2G) [cytosol] (Bos taurus)
        
        phospho-p-T287-CAMK2D [cytosol] (Bos taurus)

Signal Transduction (Bos taurus)

- MAPK family signaling cascades (Bos taurus)
  - MAPK1/MAPK3 signaling (Bos taurus)
    - RAF/MAP kinase cascade (Bos taurus)
      - RAF activation (Bos taurus)
        
        Phosphorylation of RAF (Bos taurus)
        
        RAF activating kinases [plasma membrane] (Bos taurus)
        
        p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Bos taurus)
        
        p-T286-CaMKII dodecamer [cytosol] (Bos taurus)
        
        p-T286-CAMK2A,p-T287-CAMK2B,(p-T287-CAMK2D,p-T287-CAMK2G) [cytosol] (Bos taurus)
        
        phospho-p-T287-CAMK2D [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q2HJF7

Reference Genes

BioGPS Gene:532713

ENSEMBL:ENSBTAG00000014463

KEGG:bta:532713

Monarch:532713

NCBI Gene:532713

UCSC:Q2HJF7

Reference Transcript

RefSeq:NM_001046333.1

Other Identifiers

532713

Bt.23394.1.S1_at

Bt.4901.1.S1_at

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004683

GO:0005516

GO:0005524

GO:0005737

GO:0005886

GO:0006468

GO:0010613

GO:0014069

GO:0016020

GO:0016301

GO:0016529

GO:0016740

GO:0033017

GO:0042383

GO:0043005

GO:0043226

GO:0048168

GO:0060341

GO:0106310

GO:0140096

GO:1903076

Participates

as a member of

Other forms of this molecule

phospho-p-T287-CAMK2D [plasma membrane]

phospho-p-T287-CAMK2D [nucleoplasm]

phospho-p-T287-CAMK2D [endocytic vesicle membrane]

CAMK2D [cytosol]

Inferred From

p-T287-CAMK2D [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 287 (in Homo sapiens)

Coordinate

287

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

ENSEMBL

ENSBTAT00000039835, ENSBTAG00000014463, ENSBTAP00000039621

VGNC

53692

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