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ARHGEF7 [cytosol]
Stable Identifier
R-BTA-430346
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
ARHGEF7, F1MBM9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
Ephrin signaling (Bos taurus)
GIT1 binds bPIX (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
PAK binds RAC and bPIX (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
PAKs autophosphorylate (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
PAKs phosphorylate MLC (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
bPIX exchanges GTP for GDP on RAC, activating it (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
GEFs [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
GEFs activate RhoA,B,C (Bos taurus)
GEFs [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
EGFR downregulation (Bos taurus)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
CDC42:GTP binds CBL:Beta-Pix (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
CBL:Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase cycle (Bos taurus)
RAC1 GTPase cycle (Bos taurus)
RAC1 GEFs activate RAC1 (Bos taurus)
RAC1 GEFs [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOA GTPase cycle (Bos taurus)
RHOA GEFs activate RHOA (Bos taurus)
RHOA GEFs [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOQ GTPase cycle (Bos taurus)
RHOQ binds effectors at the plasma membrane (Bos taurus)
RHOQ effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Bos taurus)
RHOQ effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOU GTPase cycle (Bos taurus)
RHOU binds effectors at the plasma membrane (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOU:GTP:RHOU effectors [plasma membrane] (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOV GTPase cycle (Bos taurus)
RHOV binds effectors at the plasma membrane (Bos taurus)
RHOV effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
RHOV:GTP:RHOV effectors [plasma membrane] (Bos taurus)
RHOV effectors [cytosol] (Bos taurus)
ARHGEF7 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MBM9
Gene Names
ARHGEF7
Reference Genes
ENSEMBL:ENSBTAG00000020726.6
UCSC:F1MBM9 ARHGEF7
Reference Transcript
RefSeq:XM_015465836.1 ARHGEF7
Other Identifiers
524352
GO:0000322
GO:0002244
GO:0005085
GO:0005773
GO:0005829
GO:0005886
GO:0019901
GO:0030027
GO:0030032
GO:0030154
GO:0043226
GO:0060124
GO:0098772
GO:0098794
Participates
as a candidate of
RHOA GEFs [cytosol] (Bos taurus)
RHOV effectors [cytosol] (Bos taurus)
RHOQ effectors [cytosol] (Bos taurus)
CDC42 effectors [cytosol] (Bos taurus)
RAC1 GEFs [cytosol] (Bos taurus)
RHOJ effectors [cytosol] (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
as an input of
GIT1 binds bPIX (Bos taurus)
as a component of
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Bos taurus)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
Beta-Pix:CDC42:GTP [cytosol] (Bos taurus)
as a member of
GEFs [cytosol] (Bos taurus)
Inferred From
ARHGEF7 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSBTAG00000020726
,
ENSBTAT00000027619
,
ENSBTAP00000027619
VGNC
26121
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