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phospho-p-S144,T423-PAK1 [cytosol]
Stable Identifier
R-BTA-399819
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
Q08E52
Locations in the PathwayBrowser
Expand all
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
Semaphorin interactions (Bos taurus)
Sema3A PAK dependent Axon repulsion (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Phosphorylation of LIMK-1 by PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
p-2Y-PAK [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Autophosphorylation of PAK1 (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1 phosphorylates LIMK1 (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Muscle contraction (Bos taurus)
Smooth Muscle Contraction (Bos taurus)
MYLK (MLCK) Active Calmodulin Binding (Bos taurus)
p-S,T-PAK1,2 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK6/MAPK4 signaling (Bos taurus)
Autophosphorylation of PAK1,2,3 (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1,2,3 phosphorylates MAPK6,4 (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated vascular permeability (Bos taurus)
PAK1-3 phosphorylates VE-cadherin (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PAKs (Bos taurus)
Autophosphorylation of PAK1,2,3 (Bos taurus)
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
FLNA binds PAK1 (Bos taurus)
p-S144,T423-PAK1:FLNA [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
MYLK (MLCK) Active Calmodulin Binding (Bos taurus)
p-S,T-PAK1,2 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1 or PAK2 phosphorylates MYLK (Bos taurus)
p-S,T-PAK1,2 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1 phosphorylates FLNA (Bos taurus)
p-S144,T423-PAK1:FLNA [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1 phosphorylates LIMK1 (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
PAK1 phosphorylates myosin phosphatase (Bos taurus)
phospho-p-S144,T423-PAK1 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q08E52
Reference Genes
BioGPS Gene:533729
ENSEMBL:ENSBTAG00000010191
KEGG:bta:533729
Monarch:533729
NCBI Gene:533729
UCSC:Q08E52
Reference Transcript
RefSeq:NM_001076898.1
RefSeq:XM_010820837.3
RefSeq:XM_010820835.3
RefSeq:XM_024987207.2
RefSeq:XM_015461133.3
RefSeq:XM_010820836.4
Other Identifiers
533729
Bt.22106.2.S1_at
Bt.5858.1.S1_at
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0006468
GO:0016740
GO:0140096
Participates
as an output of
PAK1 phosphorylates FLNA (Bos taurus)
Autophosphorylation of PAK1 (Bos taurus)
as an input of
FLNA binds PAK1 (Bos taurus)
as a component of
p-S144,T423-PAK1:FLNA [cytosol] (Bos taurus)
as a candidate of
p-S,T-PAK1,2 [cytosol] (Bos taurus)
as a member of
p-S,T-PAK1,2,3 [cytosol] (Bos taurus)
p-2Y-PAK [cytosol] (Bos taurus)
Other forms of this molecule
phospho-p-S144,T423-PAK1 [plasma membrane]
PAK1 [cytosol]
Inferred From
p-S144,T423-PAK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 144 (in Homo sapiens)
Coordinate
144
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 423 (in Homo sapiens)
Coordinate
423
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_024842975.1
,
XP_010819139.1
,
XP_015316619.1
,
XP_010819138.1
,
XP_010819137.1
,
NP_001070366.1
ENSEMBL
ENSBTAP00000013448
,
ENSBTAT00000013448
,
ENSBTAG00000010191
IntEnz
2.7.11.1
VGNC
53657
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