Reactome | PLXNA1 [plasma membrane]

PLXNA1 [plasma membrane]

Stable Identifier

R-BTA-396932

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

PLXNA1, E1BFR4

Locations in the PathwayBrowser

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Developmental Biology (Bos taurus)

- Nervous system development (Bos taurus)
  - Axon guidance (Bos taurus)
    - Semaphorin interactions (Bos taurus)
      - CRMPs in Sema3A signaling (Bos taurus)
        
        Phosphorylation of CRMPs by Cdk5 (Bos taurus)
        
        Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's [plasma membrane] (Bos taurus)
        
        NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMP tetramers [plasma membrane] (Bos taurus)
        
        PlexinA1-4:FYN:Cdk5:p35:p-CRMP tetramers [plasma membrane] (Bos taurus)
        
        Plexin-A1-4 [plasma membrane] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)
        
        Sema3A:Nrp-1:PlexinA:Fyn:pCdk5 [plasma membrane] (Bos taurus)
        
        NRP1:PlexinA1-4:FYN:pCdk5:p53 [plasma membrane] (Bos taurus)
        
        PlexinA1-4:FYN:pCdk5:p35 [plasma membrane] (Bos taurus)
        
        Plexin-A1-4 [plasma membrane] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)
        
        Phosphorylation of CRMPs by GSK3beta (Bos taurus)
        
        Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's [plasma membrane] (Bos taurus)
        
        NRP1:PlexinA1-4:FYN:Cdk5:p53:p-CRMP tetramers [plasma membrane] (Bos taurus)
        
        PlexinA1-4:FYN:Cdk5:p35:p-CRMP tetramers [plasma membrane] (Bos taurus)
        
        Plexin-A1-4 [plasma membrane] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)
      - SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Bos taurus)
        
        Sema3A binds Nrp-1 bound to PlexinA (Bos taurus)
        
        NRP1:PlexinA1-4:FARP2:FYN [plasma membrane] (Bos taurus)
        
        Plexin-A1-4:FYN:FARP2 [plasma membrane] (Bos taurus)
        
        Plexin-A1-4:FYN [plasma membrane] (Bos taurus)
        
        Plexin-A1-4 [plasma membrane] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)
        
        Sema3A:Nrp-1:Plexin A:Fyn [plasma membrane] (Bos taurus)
        
        NRP1:Plexin-A1-4:FYN [plasma membrane] (Bos taurus)
        
        Plexin-A1-4 [plasma membrane] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)

Signal Transduction (Bos taurus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
  - Signaling by Rho GTPases (Bos taurus)
    - RHO GTPase cycle (Bos taurus)
      - RND1 GTPase cycle (Bos taurus)
        
        RND1 binds effectors (Bos taurus)
        
        RND1 effectors [cytosol] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)
        
        RND1:GTP:RND1 effectors [plasma membrane] (Bos taurus)
        
        RND1 effectors [cytosol] (Bos taurus)
        
        PLXNA1 [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BFR4

Gene Names

PLXNA1

Reference Genes

BioGPS Gene:531240 PLXNA1

ENSEMBL:ENSBTAG00000009159.6

KEGG:bta:531240 PLXNA1

Monarch:531240 PLXNA1

NCBI Gene:531240 PLXNA1

UCSC:E1BFR4 PLXNA1

Reference Transcript

RefSeq:XM_024983120.2 PLXNA1

Other Identifiers

531240

GO:0002116

GO:0002291

GO:0005515

GO:0005654

GO:0005829

GO:0014910

GO:0016020

GO:0017154

GO:0021628

GO:0021828

GO:0045202

GO:0048870

GO:0060666

GO:0071526

GO:0097485

GO:0098978

GO:1990138

Participates

as a member of

Other forms of this molecule

phospho-PLXNA1 [plasma membrane]

Inferred From

PLXNA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_024838888.1

ENSEMBL

ENSBTAP00000030566, ENSBTAT00000030589, ENSBTAG00000009159

VGNC

33059

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