Reactome | alpha Actin [cytosol]

alpha Actin [cytosol]

Stable Identifier

R-BTA-390535

Type

Set [DefinedSet]

Species

Bos taurus

Compartment

cytosol

Locations in the PathwayBrowser

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Extracellular matrix organization (Bos taurus)

- Non-integrin membrane-ECM interactions (Bos taurus)
  - Formation of the dystrophin-glycoprotein complex (DGC) (Bos taurus)
    - DGC complex binds AGRN and HSPG2 (Bos taurus)
      - DGC complex:laminins:F-actin [plasma membrane] (Bos taurus)
        
        F-actin (all) [cytosol] (Bos taurus)
        
        actins:ATP [cytosol] (Bos taurus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
      - DGC complex:laminins:F-actin:AGRN,HSPG2 [plasma membrane] (Bos taurus)
        
        DGC complex:laminins:F-actin [plasma membrane] (Bos taurus)
        
        F-actin (all) [cytosol] (Bos taurus)
        
        actins:ATP [cytosol] (Bos taurus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)

Muscle contraction (Bos taurus)

- Striated Muscle Contraction (Bos taurus)
  - ATP Hydrolysis By Myosin (Bos taurus)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
  - Calcium Binds Troponin-C (Bos taurus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
    - Inactive Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
  - Myosin Binds ATP (Bos taurus)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
  - Release Of ADP From Myosin (Bos taurus)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Bos taurus)
        
        alpha Actin Chain [cytosol] (Bos taurus)
        
        alpha Actin [cytosol] (Bos taurus)

Participants

members

Participates

as a repeated unit of

alpha Actin Chain [cytosol] (Bos taurus)

as a member of

(ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Bos taurus)

Inferred From

alpha Actin [cytosol] (Homo sapiens)

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