Reactome | MC4R [plasma membrane]

MC4R [plasma membrane]

Stable Identifier

R-BTA-388606

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

Q9GLJ8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR downstream signalling (Bos taurus)
    - G alpha (s) signalling events (Bos taurus)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
        
        MSH:Melanocortin receptors [plasma membrane] (Bos taurus)
        
        Melanocortin receptors [plasma membrane] (Bos taurus)
        
        MC4R [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Bos taurus)
        
        MSH:Melanocortin receptors [plasma membrane] (Bos taurus)
        
        Melanocortin receptors [plasma membrane] (Bos taurus)
        
        MC4R [plasma membrane] (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Melanocortin receptors bind melanocortins (Bos taurus)
        
        MSH:Melanocortin receptors [plasma membrane] (Bos taurus)
        
        Melanocortin receptors [plasma membrane] (Bos taurus)
        
        MC4R [plasma membrane] (Bos taurus)
        
        Melanocortin receptors [plasma membrane] (Bos taurus)
        
        MC4R [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q9GLJ8

Reference Genes

BioGPS Gene:281300

ENSEMBL:ENSBTAG00000019676

KEGG:bta:281300

Monarch:281300

NCBI Gene:281300

UCSC:Q9GLJ8

Reference Transcript

RefSeq:NM_174110.1

Other Identifiers

281300

Bt.5561.1.S1_at

GO:0004930

GO:0004977

GO:0004980

GO:0007186

GO:0007189

GO:0007631

GO:0016020

GO:0030073

GO:0031625

GO:0032094

GO:0032868

GO:0042923

GO:0045780

GO:1903998

GO:1990680

Participates

as a member of

Melanocortin receptors [plasma membrane] (Bos taurus)

Inferred From

MC4R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_776535.1

ENSEMBL

ENSBTAG00000019676, ENSBTAP00000026223, ENSBTAT00000026223

VGNC

31295

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